| 2024 |
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|---|
| 345. Sirui Shen, Zhuqi Huang, Yudie Yang, Jibo Han, Zimin Fang, Jiachen Xu, Yue Guan, Julian Min, Yi Wang, Gaojun Wu, Wu Luo*, Zhouqing Huang*, Guang Liang*. JOSD2 inhibits angiotensin II-induced vascular remodeling by deubiquitinating and stabilizing SMAD7. Acta Pharmacologica Sinica,2024,Accepted.(一区，IF=6.9） [暂无下载] |
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344. Weiwei Zhu#, Qianhui Zhang#, Leiming Jin#, Shuaijie Lou, Jiaxi Ye, Yaqian Cui, Yongqiang Xiong, Mengsha Lin, Guang Liang*, Wu Luo*, Zaishou Zhuang*. OTUD1 Deficiency Alleviates LPS-Induced Acute Lung Injury in Mice by Reducing Inflammatory Response.Inflammation,2024,Accepted.(二区，IF=4.5） [  PDF DOWNLOAD] |
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| 343. Lijun Ji, Shuaijie Lou, Yi Fang, Xu Wang, Weiwei Zhu, Guang Liang, Kwangyoul Lee, Wu Luo*, Zaishou Zhuang*. Patchouli Alcohol Protects the Heart against Diabetes-Related Cardiomyopathy through the JAK2/STAT3 Signaling Pathway. Pharmaceuticals,2024,17(5):631.(三区，IF=4.3） [ PDF DOWNLOAD] |
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| 342. Jibo Han#, Liming Lin#, Zimin Fang#, Bozhi Ye, Xue Han, Jiachen Xu, Binjiang Han, Julian Min, Jinfu Qian, Gaojun Wu, Yi Wang*, Guang Liang*. Cardiomyocyte-derived USP28 negatively regulates antioxidant response and promotes cardiac hypertrophy via deubiquitinating TRIM21. Theranostics,2024,Accepted.(一区，IF=12.4） [暂无下载] |
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| 341. Sujing Xu, Chenghong Hu, Jibo Han, Wu Luo, Lijiang Huang, Yongsheng Jiang, Aleksandr V. Samorodov, Yi Wang *, Jianxiong Huang*.Schisandrin B alleviates angiotensin II-induced cardiac inflammatory remodeling by inhibiting the recruitment of MyD88 to TLRs in mouse cardiomyocytes. Int Immunopharmacol,2024,139:112660.(二区，IF=4.8） [PDF DOWNLOAD] |
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| 340. Yanghao Chen#, Bozhi Ye#, Diyun Xu#, Wante Lin, Zimin Fang, Xuefeng Qu, Xue Han, Wu Luo, Chen Chen, Weijian Huang, Hao Zhou, Gaojun Wu, Yi Wang*, Guang Liang*. USP25 ameliorates vascular remodeling by deubiquitinating FOXO3 and promoting autophagic degradation of FOXO3. Acta Pharmaceutica Sinica B,2024,Accepted.(一区，IF=14.5） [暂无下载] |
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| 339. Jinfu Qian#, Qinyan Wang#, Jiachen Xu#, Shiqi Liang, Qingsong Zheng, Xiaocheng Guo, Wu Luo, Weijian Huang, Xiaohong Long, Julian Min, Yi Wang, Gaojun Wu*, Guang Liang*. Macrophage OTUD1-CARD9 axis drives Isoproterenol-induced inflammatory heart remodeling. Clinical and Translational Medicine,2024,Accepted.(一区，IF=7.9） [暂无下载] |
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| 338. Ying Zhao#, Shijie Fan#, Hong Zhu#, Qingqing Zhao, Zimin Fang, Diyun Xu, Wante Lin, Liming Lin, Xiang Hu, Gaojun Wu, Julian Min, Guang Liang*. Podocyte OTUD5 alleviates diabetic kidney disease through deubiquitinating TAK1 and reducing podocyte inflammation and injury. Nature Communications,2024,Accepted.(一区，IF=14.7） [暂无下载] |
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| 337. Chenchen Qian, Weiwei Zhu, Jiong Wang, Zhe Wang, Weiyang Tang, Xin Liu, Bo Jin, Yong Xu, Yuyang Zhang, Guang Liang, Yi Wang*.Cyclic-di-GMP induces inflammation and acute lung injury through direct binding to MD2. Clinical and Translational Medicine,2024,Accepted.(一区，IF=10.6） [暂无下载] |
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| 336. Yu Zou, Xiemin Wang, Pan Chen, Zhiwei Zheng, Xiaobo Li, Zhichao Chen, Mi Guo, Ying Zhou, Chenhui Sun, Ran Wang, Wufu Zhu, Pengwu Zheng, Won-Jea Cho, Young-Chang Cho, Guang Liang *,Qidong Tang *. Fragment-Based Anti-inflammatory Agent Design and Target Identification: Discovery of AF-45 as IRAK4 Inhibitor to Treat Ulcerative Colitis and Acute Lung Injury. Journal of Medicinal Chemistry,2024,Accepted.(一区，IF = 7.3） [暂无下载] |
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| 335. Bozhi Ye#, Yanghao Chen#, Xudong Chen#, Yuchen Jiang, Wante Lin, Danhong Fang, Jiachen Xu, Jibo Han, Xue Han, Xiaohong Long, Wei Wang, Hao Zhou, Gaojun Wu*, Guang Liang*. Deubiquitinase USP25 Alleviates Obesity-Induced Cardiac Remodeling and Dysfunction by Down-Regulating TAK1 and Reducing TAK1-Mediated Inflammation. JACC-Basic to Translational Science,2024,Accepted.(一区，IF=9.7） [暂无下载] |
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| 334. Xianzhi Liu, Luyan Shen, Lin Zhou, Wencheng Wu, Guang Liang*,Yunjie Zhao*, Wenqi Wu*. Nucleotides as new co-formers in co-amorphous systems: Enhanced dissolution rate, water solubility and physical stability. European Journal of Pharmaceutics and Biopharmaceutics,2024,200,114333.(二区，IF=4.9） [PDF DOWNLOAD] |
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| 333. Diyun Xu#, Bozhi Ye#, Liming Lin, Yanhong Jin, Yuchen Jiang, Zhaozheng Zheng, Yanghao Chen, Xue Han, Wei Wang, Gaojun Wu, Zaishou Zhuang*, Peiren Shan*, Guang Liang*. Carnosol attenuates angiotensin II-induced cardiac remodeling and inflammation via directly binding to p38 and inhibiting p38 activation. International Immunopharmacology,2024,Accepted.(二区, IF=5.6） [暂无下载] |
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| 332. Shuaijie Lou, Weiwei Zhu, Tianxiang Yu, Qianhui Zhang, Minxiu Wang, Leiming Jin, Yongqiang Xiong, Jiachen Xu, Qinyan Wang, Gaozhi Chen, Guang Liang*, Xiang Hu*, Wu Luo*. Compound SJ-12 attenuates streptozocin-induced diabetic cardiomyopathy by stabilizing SERCA2a. BBA - Molecular Basis of Disease,2024,1870(5):167140.(二区，IF=6.2） [ PDF DOWNLOAD] |
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| 331. Wante Lin#, Yucheng Jiang#, Yilin Mei, Yanghao Chen, Zhaozheng Zheng, Xue Han, Gaojun Wu, Weijian Huang*, Bozhi Ye*, Guang Liang*. Endothelial deubiquinatase YOD1 mediates Ang II-induced vascular endothelial-mesenchymal transition and remodeling by regulating β-catenin. Acta Pharmacologica Sinica,2024,Accepted.(一区，IF= 8.2） [暂无下载] |
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| 330. Zimin Fang#, Jibo Han#, Liming Lin, Bozhi Ye, Xuefeng Qu, Yu Zhang, Ying Zhao, Diyun Xu, Wante Lin, Sirui Shen, Julian Min, Gaojun Wu, Zhouqing Huang*, Guang Liang*. Deubiquitinase OTUD6a drives cardiac inflammation and hypertrophy by deubiquitination of STING. BBA - Molecular Basis of Disease,2024,1870:167061.(二区，IF=6.2） [PDF DOWNLOAD] |
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| 329. Ying Zhou #, Zhiteng Du #, Qianqian Wu, Mi Guo, Zhichao Chen, Chenhui Sun, Xiaobo Li, Yu Zou, Zhiwei Zheng, Pan Chen, Won-Jea Cho, Young-Chang Cho, Nipon Chattipakorn, Yi Wang *, Guang Liang *, Qidong Tang *. Discovery of novel osthole derivatives exerting anti-inflammatory effect on DSS-induced ulcerative colitis and LPS-induced acute lung injury in mice. European Journal of Medicinal Chemistry,2024,116252.(一区，IF= 6.7） [PDF DOWNLOAD] |
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| 328. Chenchen Qian#, Diyun Xu#, Jiong Wang, Yue Luo, Tianyang Jin, Lijiang Huang, Yafen Zhou, Zhaohong Cai, Bo Jin, Hongdan Bao*, Yi Wang*. Toll-like receptor 2 deficiency ameliorates obesity-induced cardiomyopathy via inhibiting NF-κB signaling pathway. International Immunopharmacology,2024,128:111551.(二区, IF=5.6） [PDF DOWNLOAD] |
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| 327. Yanni Zhao, Zhoudi Liu, Tao Yan, Tingxin Xu, Tianyang Jin, Yongsheng Jiang, Wei Zuo, Kwang Youl Lee*, Lijiang Huang*, Yi Wang*. Macrophage-specific FGFR1 deletion alleviates high-fat-diet-induced liver inflammation by inhibiting the MAPKs/TNF pathways. Acta Pharmacologica Sinica,2024,Accepted.(一区，IF= 8.2） [暂无下载] |
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| 326. Xiong Chen#, Jinfu Qian#, Shiqi Liang, Jianchang Qian, Wu Luo, Yujuan Shi, Hong Zhu, Xiang Hu, Gaojun Wu, Xiaokun Li, Guang Liang*. Hyperglycemia activates FGFR1 via TLR4/c-Src pathway to induce inflammatory cardiomyopathy in diabetes. Acta Pharmaceutica Sinica B,2024,14(4):1693-1710.(一区，IF=14.5） [PDF DOWNLOAD] |
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| 325. Qinyan Wang, Shiqi Liang, Jinfu Qian, Jiachen Xu, Qingsong Zheng, Mengyang Wang, Xiaochen Guo, Julian Min, Gaojun Wu, Zaishou Zhuang, Wu Luo*, Guang Liang*. OTUD1 Promotes Isoprenaline- and Myocardial Infarction-induced Heart Failure by Targeting PDE5A in Cardiomyocytes. BBA - Molecular Basis of Disease,2024,167018.(一区，IF=6.2） [PDF DOWNLOAD] |
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| 324. Jingjing Shao#, Weifeng Li#, Jinfeng Sun, Zaishou Zhuang, Julian Min, Xiaohong Long, Gaojun Wu, Haowen Xu*, Guang Liang*. Britannin as a novel NLRP3 inhibitor, suppresses inflammasome activation in macrophages and alleviates NLRP3-related diseases in mice. Acta Pharmacologica Sinica,2024,45:803-814.(一区，IF= 8.2） [PDF DOWNLOAD] |
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| 323. Xin Liu#, Yi Fang#, Chenchen Qian, Jiahao Chen, Wu Luo, Wei Zuo, Jianjun Lin, Longteng Xie, Guang Liang, Lijiang Huang*, Yi Wang*. CARD9 deficiency aggravated nonalcoholic steatohepatitis in mice through increasing inflammatory response. BBA-Molecular Basis of Disease,2024,1870(1): 166893.(一区，IF=6.2） [PDF DOWNLOAD] |
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| 322. Jiachen Xu, Shiqi Liang, Qinyan Wang, Qingsong Zheng, Mengyang Wang, Jinfu Qian, Tianxiang Yu, Shuaijie Lou, Wu Luo*, Hao Zhou*, Guang Liang*. JOSD2 mediates Isoprenaline-induced Heart Failure by Deubiquitinating CaMKIIδ in Cardiomyocytes. Cellular and Molecular Life Sciences,2024,Jan 10;81(1):18.(一区，IF=8.0） [PDF DOWNLOAD] |
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| 321. Lijun Ji, Xiaojing Yang, Yiyi Jin, Li Li, Bin Yang, Weiwei Zhu, Mingjiang Xu, Yi Wang, Gaojun Wu, Wu Luo*, Kwangyoul Lee*, Guang Liang*. Blockage of DCLK1 in cardiomyocytes suppresses myocardial inflammation and alleviates diabetic cardiomyopathy in streptozotocin-induced diabetic mice. BBA - Molecular Basis of Disease,2024;1870(1): 166900.(一区，IF=6.2） [PDF DOWNLOAD] |
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| 317. Jinfu Qian#, Shiqi Liang#, Qinyan Wang, Jiachen Xu, Wu Luo, Weijian Huang, Gaojun Wu*, Guang Liang*. Isoproterenol induces MD2 activation by β-AR-cAMP-PKA-ROS signaling axis in cardiomyocytes and macrophages drives inflammatory heart failure. Acta Pharmacologica Sinica,2024,Accepted.(一区，IF= 8.2） [PDF DOWNLOAD] |
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| 293. Lingxi Zhang, Chenghong Hu, Bo Jin, Bin Bai, Jing Liao, Leiming Jin, Minxiu Wang, Weiwei Zhu, Xuedan Wu, Li Zheng, Xuelian Xu, Yongsheng Jiang, Yi Wang*, Ying He*. Bicyclol alleviates streptozotocin-induced diabetic cardiomyopathy by inhibiting chronic inflammation. Cardiovascular Drugs and Therapy,2024,Accepted. (三区，IF=3.947）[PDF DOWNLOAD] |
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| 2023 |
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|---|
| 320. Xue Han*, Wenwei Zhou*, Jiajia Zhang, Yu Tu, Jiajia Wei, Ruyi Zheng, Jian Zhu, Diyun Xu, Huazhong Ying, Gaojun Wu, Qiaojuan Shi#, Guang Liang#. Linderalactone mitigates diabetic cardiomyopathy in mice via suppressing the MAPK/ATF6 pathway. International Immunopharmacology, 2023, 124: 110984.(二区，IF=5.58） [PDF DOWNLOAD] |
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| 319. Bo Jin, Yi Chen, Jiong Wang, Yue Chen, Mengpei Zhang, Jianxiong Huang, Yi Wang*.Costunolide alleviates hyperglycaemia-induced diabetic cardiomyopathy via inhibiting inflammatory responses and oxidative stress. Journal of Cellular and Molecular Medicine,2023,27(6): 831-845.(二区，IF= 5.3） [PDF DOWNLOAD] |
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| 318. Qianhui Zhang#, Weiwei Zhu#, Shuaijie Lou, Hongdan Bao, Yafen Zhou, Zhaohong Cai, Jiaxi Ye, Yaqian Cui, Minxiu Wang, Leiming Jin, Guang Liang , Wu Luo*, Yi Wang*. Compound c17 alleviates inflammatory cardiomyopathy in streptozotocin-induced diabetic mice by targeting MyD88. International Immunopharmacology,2023,124:110863.(二区，IF=5.58） [PDF DOWNLOAD] |
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| 316. Zhiwei Zheng, Zhichao Chen, Ying Zhou, Yu Zou, Xiaojian Shi, Xiaobo Li, Jing Liao,Jun Yang, Xiang Li, Jintian Dai, Yuye Xu, Nipon Chattipakorn, Won-Jea Cho,Qidong Tang, Guang Liang, Wenqi Wu. Synthesis and SAR study of novel diimide skeleton compounds with the anti-inflammatory activities in vitro and in vivo. Bioorganic & Medicinal Chemistry,2023, 90, 117353.(二区， IF=3.5） [PDF DOWNLOAD] |
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| 315. Jing Liao, Jun Yang, Xiaobo Li, Chenghong Hu, Weiwei Zhu, Ying Zhou, Yu Zou, Mi Guo, Zhichao Chen, Xiang Li, Jintian Dai, Yuye Xu, Zhiwei Zheng, Pan Chen, Won-Jea Ch, Guang Liang *, Qidong Tang *. Discovery of diphenyl 6-oxo-1,6-dihydropyridazine-3-carboxylate/carboxamide analogues J27 for the treatment of ALI and sepsis by targeting JNK2 and inhibiting JNK2-NF-κB/MAPK pathway. Journal of Medicinal Chemistry,2023; 66(17): 12304-12323.(一区，IF=8.04） [PDF DOWNLOAD] |
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| 314. Ying Zhao, Jing Ruan, Zhongding Li, Xian Su, Kangmin Chen, Yimin Lin, Yuepiao Cai, Peng Wang, Baohua Liu, Dirk Schlüter, Guang Liang*, Xu Wang*. OTUB1 inhibits breast cancer by non-canonically stabilizing CCN6. Clinical and Translational Medicine,2023;13: e1385.(一区，IF=10.6） [PDF DOWNLOAD] |
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| 313. Pan Chen, Jun Yang, Ying Zhou, Xiaobo Li, Yu Zou, Zhiwei Zheng, Mi Guo, Zhichao Chen, Won-Jea Cho, Nipon Chattipakorn, Wenqi Wu*, Qidong Tang*, Guang Liang*. Design, synthesis, and bioactivity evaluation of novel amide/sulfonamide derivatives as potential anti-inflammatory agents against acute lung injury and ulcerative colitis. European Journal of Medicinal Chemistry,2023;259:115706.(一区，IF=6.7） [PDF DOWNLOAD] |
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| 312. Jiong Wang, Chenchen Qian, Yue Chen, Tianyang Jin, Yongsheng Jiang, Lijiang Huang, Xinyan Fu, Dong Yang, Leiming Jin, Bo Jin, Yi Wang*.β-elemene alleviates hyperglycemia-induced cardiac inflammation and remodeling by inhibiting the JAK/STAT3-NF-κB pathway. Phytomedicine,2023;119:154987.(一区，IF=7.9） [PDF DOWNLOAD] |
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| 311. Zhiren Zou, Qiang Huang, Xiaobo Li, Xianzhi Liu, Lina Yin, Yunjie Zhao*,Guang Liang*, Wenqi Wu*.Dissolution changes in drug-amino acid/biotin co-amorphous systems:Decreased/increased dissolution during storage without recrystallization. European Journal of Pharmaceutical Sciences,2023,188,106526.(二区，IF=5.11）[PDF DOWNLOAD] |
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| 310. Jibo Han#, Zimin Fang#, Bingjiang Han, Bozhi Ye, Wante Lin, Yucheng Jiang, Xue Han, Xu Wang, Gaojun Wu, Yi Wang*, Guang Liang*. Deubiquitinase JOSD2 improves calcium handling and attenuates cardiac hypertrophy and dysfunction through stabilizing SERCA2a in cardiomyocytes. Nature Cardiovascular Research,,2023;2:764–777. [PDF DOWNLOAD] |
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| 309. Weixin Li, Yue Luo, Zhuqi Huang, Siyuan Shen, Chengyi Dai, Sirui Shen, Guang Liang *, Wu Luo*. Costunolide protected myocardial from ischemia reperfusion injury by inhibiting oxidative stress through activation of Nrf2/Keap1 pathway. Journal of Cardiovascular Pharmacology,2023;82(2):117-127. (四区，IF= 3.27）[PDF DOWNLOAD] |
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| 308. Miao Ren, Jiahao Chen, Haowen Xu, Weifeng Li, Tingting Wang, Zhanghuan Chi, Yi Lin, Anqi Zhang, Gaozhi Chen, Xu Wang, Xiaoyu Sun, Guang Liang*, Junlu Wang*, Wu Luo*. Ergolide covalently binds NLRP3 and inhibits NLRP3 inflammasome-mediated pyroptosis. International ImmunoPharmacology,2023; 120, 110292. (二区，IF= 5.71）[PDF DOWNLOAD] |
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| 307. Tingting Yuan, Honglin Tang, Xiaojie Xu, Jingjing Shao, Gaojun Wu, Young-Chang Cho*, Yuan Ping*, and Guang Liang*. Inflammation Conditional Genome Editing Mediated by the CRISPR/Cas9 System. iScience,2023;26(6):106872. (二区，IF=6.11）[PDF DOWNLOAD] |
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| 306. Bo Jin, Jiong Wang, Yi Chen, Wei Zuo, Bo Hong，Jie Li, Fang Huang, Mengpei Zhang*, Yi Wang*.Focal adhesion kinase induces cardiac remodeling through NF-κB-mediated inflammatory responses in diabetic cardiomyopathy. International ImmunoPharmacology,2023;120:110280. (二区，IF=5.71）[PDF DOWNLOAD] |
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| 305. Pan Chen, Ying Zhou, Xiaobo Li, Jun Yang, Zhiwei Zheng, Yu Zou, Xiang Li, Jing Liao, Jintian Dai, Yuye Xu, Lina Yin, Gaozhi Chen, Jing Gu, Qin Ouyang, Nipon Chattipakorn, Won-Jea Cho*, Qidong Tang*, Guang Liang*. Design, synthesis, and bio-evaluation of novel MyD88 inhibitor c17 against acute lung injury derived from the virtual screen. Journal of Medicinal Chemistry,2023;66(10):6938-6958. (一区，IF=8.04）[PDF DOWNLOAD] |
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| 304. Zhiwei Zheng#, Xiaobo Li#, Pan Chen, Yu Zou, Xiaojian Shi, Xiang Li, Eun Young Kim, Jing Liao, Jun Yang, Nipon Chattipakorn, Gaojun Wu, Qidong Tang*, Won-Jea Cho*, Guang Liang*. Design and synthesis optimization of novel diimide indoles derivatives for ameliorating acute lung injury through modulation of NF-κB signaling pathway. Bioorganic Chemistry, 2023,136:106557. (一区，IF=5.3）[PDF DOWNLOAD] |
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| 303. Ying Zhao, Xi Chen, Yimin Lin, Xian Su, Shijie Fan, Yanghao Chen, Xu Wang* , Guang Liang*. USP25 inhibits renal fibrosis by regulating TGFβ-SMAD signaling pathway in Ang II-induced hypertensive mice. BBA - Molecular Basis of Disease,2023,1869:166713. (一区，IF=6.63）[PDF DOWNLOAD] |
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| 302. Na Yang, Minxiu Wang, Ke Lin, Mengyang Wang, Diyun Xu, Xue Han, Xia Zhao, Yi Wang, Wu Luo, Gaojun Wu, Guang Liang*, Peiren Shan*. Dectin-1 deficiency alleviates diabetic cardiomyopathy by attenuating macrophage-mediated inflammatory response. BBA - Molecular Basis of Disease,2023;1869(6):166710. (一区，IF=6.63）[PDF DOWNLOAD] |
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| 301. Weixin Li, Zhuqi Huang, Yue Luo, Yaqian Cui, Mingjiang Xu, Wu Luo, Gaojun Wu*, Guang Liang*. Tetrandrine alleviates atherosclerosis via inhibition of STING-TBK1 pathway and inflammation in macrophages. International ImmunoPharmacology,2023;119:110139. (二区，IF=5.71）[PDF DOWNLOAD] |
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| 300. Sirui Shen, Zhuqi Huang, Liming Lin, Zimin Fang, Weixin Li, Wu Luo, Gaojun Wu, Zhouqing Huang*, Guang Liang*. Tussilagone attenuates atherosclerosis through inhibiting MAPKs-mediated inflammation in macrophages. International ImmunoPharmacology,2023;119:110066. (二区，IF=5.71）[PDF DOWNLOAD] |
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| 299. Xiang Li, Lina Yin, Jing Liao, Jun Yang, Binhao Cai, Yiming Yu, Sijia Su, Zhiteng Du, Xiaobo Li, Ying Zhou, Pan Chen, Won-Jea Cho, Nipon Chattipakorn, Aleksandr V. Samorodov, Valentin N. Pavlov, Fengzhi Zhang*, Guang Liang*, Qidong Tang*. Novel O-benzylcinnamic acid derivative L26 Treats Acute Lung Injury in Mice by MD-2. European Journal of Medicinal Chemistry,2023;252:115289. (一区，IF=7.088）[PDF DOWNLOAD] |
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| 298. Xin Liu, Yi Fang, Xinting Lv, Chenghong Hu, Guorong Chen, Lingxi Zhang, Bo Jin, Lijiang Huang, Wu Luo, Guang Liang, Yi Wang*. Deubiquitinase OTUD6A in macrophages promotes intestinal inflammation and colitis via deubiquitination of NLRP3. Cell Death & Differentiation, 2023;30(6):1457-1471. (一区，IF=12.07）[PDF DOWNLOAD] |
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| 297. Zhuqi Huang, Sirui Shen, Xue Han, Weixin Li, Wu Luo, Liming Lin, Mingjiang Xu, Yi Wang, Weijian Huang, Gaojun Wu, Guang Liang*. Macrophage DCLK1 promotes atherosclerosis via binding to IKKβ and inducing inflammatory responses. EMBO Molecular Medicine,2023;15(5):e17198. (一区，IF=14.3）[PDF DOWNLOAD] |
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| 296. Wu Luo, Yiyi Jin, Yuchen Jiang, Libin Yang, Haowen Xu, Di Wu, Yanmei Zhang, Lina Yin, Zia A. Khan, Guang Liang*, Yi Wang*. Doublecortin-like kinase 1 activates NF-κB to induce inflammatory responses by binding directly to IKKβ. Cell Death and Differentiation,2023;30(5):1184-1197. (一区，IF=12.07）[PDF DOWNLOAD] |
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| 295. Qiang Huang, Zhiren Zou, Xiaobo Li, Qinwen Xiao, Guang Liang*, Wenqi Wu*. Poly (amino acid)s as new co-formers in amorphous solid dispersion. International Journal of Pharmaceutics,2023,634,22645. (二区，IF= 6.51）[PDF DOWNLOAD] |
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| 294. Jun Yang, Minxiu Wang, Yulan Xu, Jing Liao, Xiang Li, Ying Zhou, Jintian Dai, Xiaobo Li, Pan Chen, Gaozhi Chen, Won-Jea Cho, Nipon Chattipakorn, Aleksandr V. Samorodov, Valentin N. Pavlov, Yi Wang*, Guang Liang*, Qidong Tang*. Discovery of 4-oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide Derivatives as Novel Anti-inflammatory Agents for the Treatment of Acute Lung Injury and Sepsis. European Journal of Medicinal Chemistry,2023,249,115144. (一区，IF= 7.088）[PDF DOWNLOAD] |
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| 292. Chenchen Qian, Jiong Wang, Wante Lin, Yanghao Chen, Jie Yang, Min Liu, Xiaoyu Sun, Hongbo Wu, Mengpei Zhang, Yi Wang*, Shan Cao*. Tabersonine attenuates obesity-induced renal injury via inhibiting NF-κB-mediated inflammation. Phytotherapy Research,2023;37(6):2353-2363. (二区，IF= 6.38）[PDF DOWNLOAD] |
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| 291. Bozhi Ye, Hao Zhou, Yanghao Chen , Wu Luo, Wante Lin, Ying Zhao, Jibo Han, Xue Han, Weijian Huang, Gaojun Wu, Xu Wang*, Guang Liang*. USP25 Ameliorates Pathological Cardiac Hypertrophy by Stabilizing SERCA2a in Cardiomyocytes. Circulation Research,2023;132(4):465-480. (一区，IF= 23.2）[PDF DOWNLOAD] |
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| 290. Weifeng Li#, Haowen Xu#, Jingjing Shao, Jiahao Chen, Yimin Lin, Zhiwei Zheng, Yi Wang, Wu Luo*, Guang Liang*. Discovery of alantolactone as a natural NLRP3 inhibitor to alleviate NLRP3-driven inflammatory diseases in mice. British Journal of Pharmacology,2023;180(12):1634-1647. (一区，IF= 9.47）[PDF DOWNLOAD] |
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| 289. Jinfu Qian#, Shiqi Liang#, Qinyan Wang#, Jiachen Xu, Weijian Huang, Gaojun Wu*, Guang Liang*. Toll-like receptor-2 in cardiomyocytes and macrophages mediates isoproterenol-induced cardiac inflammation and remodeling. FASEB Journal,2023,37(2):e22740. (二区，IF=5.83）[PDF DOWNLOAD] |
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| 288. Zhuqi Huang, Sirui Shen, Mengyang Wang, Weixin Li, Gaojun Wu, Weijian Huang, Wu Luo, Guang Liang*. Mouse endothelial OTUD1 promotes Ang II-induced vascular remodeling by deubiquitinating SMAD3. EMBO Reports,2023;24(3):e56135. (一区，IF=9.07）[PDF DOWNLOAD] |
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| 287. Leiming Jin, Minxiu Wang, Bin Yang, Lin Ye, Weiwei Zhu, Qianhui Zhang, Shuaijie Lou, Yi Zhang, Wu Luo, Guang Liang*. A small-molecule JNK inhibitor JM-2 attenuates high-fat diet-induced non-alcoholic fatty liver disease in mice. International ImmunoPharmacology,2023,115:109587. (二区，IF=5.71）[PDF DOWNLOAD] |
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| 286. Pan Chen, Yiming Yu, Sijia Su, Zhiteng Du, Binhao Cai, Xiaoyu Sun, Nipon Chattipakorn, Aleksandr V. Samorodov, Valentin N. Pavlov, Qidong Tang*, Won-Jea Cho*. Guang Liang*. Design, synthesis, and bioactivity evaluation of novel 1-(4-(benzylsulfonyl)-2-nitrophenyl) derivatives as potential anti-inflammatory agents against LPS-induced acute lung injury. Bioorganic & Medicinal Chemistry Letters,2023;80:129097. (三区，IF= 2.94）[PDF DOWNLOAD] |
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| 285. Haowen Xu#, Weifeng Li#, Shanshan Hong#, Jingjing Shao, Jiahao Chen, Nipon Chattipakorn, Di Wu*, Wu Luo*, Guang Liang*. Tabersonine, a natural NLRP3 inhibitor, suppresses inflammasome activation in macrophages and attenuate NLRP3-driven diseases in mice. Acta Pharmacologica Sinica,2023;44(6):1252-1261. (一区，IF= 7.17）[PDF DOWNLOAD] |
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| 284. Bozhi Ye#, Xudong Chen#, Yanghao Chen, Wante Lin, Diyun Xu, Zimin Fang, Nipon Chattipakorn, Weijian Huang, Xu Wang, Gaojun Wu*, Guang Liang*. Inhibition of TAK1/TAB2 Complex Formation by Costunolide Attenuates Obesity Cardiomyopathy via the NF-κB Signaling Pathway. Phytomedicine,2023,108:154523. (一区，IF= 6.66）[PDF DOWNLOAD] |
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| 283. Siyuan Shen, Gaojun Wu, Wu Luo, Weixin Li, Xiaobo Li, Chengyi Dai, Weijian Huang*, Guang Liang*. Leonurine attenuates angiotensin II-induced cardiac injury and dysfunction via inhibiting MAPK and NF-κB pathway. Phytomedicine,2023,108:154519. (一区，IF= 6.66）[PDF DOWNLOAD] |
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| 279. Weiwei Zhu#, Wu Luo#, Jibo Han, Qiuyan Zhang, Lijun Ji, Aleksandr V. Samorodov, Valentin N. Pavlov, Zaishou Zhuang, Daona Yang, Lina Yin, Lijiang Huang, Guang Liang, Joo Young Huh*, Yi Wang*. Schisandrin B protects against LPS-induced inflammatory lung injury by targeting MyD88. Phytomedicine,2023, 108:154489. (一区，IF= 6.66）[PDF DOWNLOAD] |
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| 277. Yanghao Chen, Wante Lin, Pan Chen, Bozhi Ye, Wu Luo, Xu Wang, Weijian Huang, Gaojun Wu*, Guang Liang*. Tabersonine alleviates obesity-induced cardiomyopathy by binding to TAK1 and inhibiting TAK1-mediated inflammation. Phytotherapy Research,2023;37(3):860-871. (二区，IF= 6.38）[PDF DOWNLOAD] |
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| 276. Na Yang#, Chunpeng Zou#, Wu Luo, Diyun Xu, Mengyang Wang, Yi Wang, Gaojun Wu, Peiren Shan*, Guang Liang*. Sclareol attenuates angiotensin II-induced cardiac remodeling and inflammation via inhibiting MAPK signaling. Phytotherapy Research,2023;37(2):578-591. (二区，IF= 6.38）[PDF DOWNLOAD] |
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| 274. Haowen Xu, Jiahao Chen, Pan Chen, Weifeng Li, Jingjing Shao, Shanshan Hong, Yi Wang, Lingfeng Chen, Wu Luo*, Guang Liang*. Costunolide covalently targets NACHT domain of NLRP3 to inhibit inflammasome activation and alleviate NLRP3-driven inflammatory diseases. Acta Pharmaceutica Sinica B,2023,13(2): 678-693. (一区，IF= 14.9）[PDF DOWNLOAD] |
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| 272. Weiwei Zhu, Minxiu Wang, Leiming Jin, Bin Yang, Bin Bai, Rumbidzai Natasha Mutsinze, Wei Zuo, Nipon Chattipakorn, Joo Young Huh*, Guang Liang*, Yi Wang*. Licochalcone A protects against LPS-induced inflammation and acute lung injury by directly binding with MD2. British Journal of Pharmacology,2023;180(8):1114-1131. (一区，IF= 9.47）[PDF DOWNLOAD] |
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| 267. Yanghao Chen, Wante Lin, Lingfeng Zhong, Zimin Fang, Bozhi Ye, Zhe Wang, Nipon Chattipakorn, Weijian Huang*, Guang Liang*, Gaojun Wu*. Bicyclol Attenuates Obesity-induced Cardiomyopathy via Inhibiting NF-κB and MAPK Signaling Pathways. Cardiovascular Drugs and Therapy,2023;37(6):1131-1141. (二区，IF= 3.94）[PDF DOWNLOAD] |
|
| 264. Zhuqi Huang#, Wu Luo#, Weixin Li, Pan Chen, Zhe Wang, Ruijie Chen, Yi Wang, Weijian Huang*, Guang Liang*. Costunolide alleviates atherosclerosis through inhibiting NF-κB-mediated inflammation via covalently binding to IKKβ. Acta Pharmacologica Sinica,2023,44(1): 58–70. (一区，IF= 7.17）[PDF DOWNLOAD] |
|
| 262. Minxiu Wang#, Wu Luo#, Lin Ye, Leiming Jin, Bin Yang, Qianhui Zhang, Jianchang Qian, Yi Wang, Yi Zhang, Guang Liang*. Dectin-1 plays a deleterious role in high fat diet-induced NAFLD of mice through enhancing macrophage activation. Acta Pharmacologica Sinica,2023,44(1):120-132. (一区，IF= 7.17）[PDF DOWNLOAD] |
|
| 2022 |
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|---|
| 282. Pengqin Chen#, Zhengwei Xu#, Xiemin Wang, Jie He, Jun Yang, Jun Wang, Nipon Chattipakorn, Di Wu, Qidong Tang *, Guang Liang *, Ting Chen *. Discovery of New Cinnamic Derivatives as Anti-inflammatory Agents for treating Acute Lung Injury in mice. Archiv der Pharmazie,2022: e2200191. (三区，IF= 4.613）[PDF DOWNLOAD] |
|
| 281. Chenghong Hu, Yue Chen, Lingxi Zhang, Min Liu, Jie Yang, Fang Huang, Yi Wang*, Lijiang Huang*. Curcumin analog C66 alleviates inflammatory colitis by inhibiting the activation of NF-κB. Inflammopharmacology,2022,30:2167-79. (二区，IF= 5.09）[PDF DOWNLOAD] |
|
| 280. Wu Luo#, Gaojun Wu#, Xiaojun Chen, Qiuyan Zhang, Chunpeng Zou, Jun Wang, Jun Liu, Nipon Chattipakorn, Yi Wang, Guang Liang*. Blockage of MyD88 in cardiomyocytes alleviates cardiac inflammation and cardiomyopathy in experimental diabetic mice. Biochemical Pharmacology,2022,206:115292. (二区，IF= 6.1）[PDF DOWNLOAD] |
|
| 278. Jianjun Lin, Ke Lin, Lijiang Huang, Yongsheng Jiang, Xiaoxiao Ding, Wu Luo, Aleksandr V Samorodov, Valentin N Pavlov, Guang Liang, Jianchang Qian*, Yi Wang*. Heme induces inflammatory injury by directly binding to the complex of myeloid differentiation protein 2 and toll-like receptor 4. Toxicology Letters,2022,370:15-23. (二区，IF= 4.271）[PDF DOWNLOAD] |
|
| 275. Wu Luo#, Ke Lin#, Junyi Hua#, Jibo Han, Qiuyan Zhang, Lingfeng Chen, Zia A. Khan, Gaojun Wu, Yi Wang, Guang Liang*. Schisandrin B attenuates diabetic cardiomyopathy by targeting MyD88 and inhibiting MyD88-dependent inflammation. Advanced Science,2022,9:2202590. (一区，IF= 17.5）[PDF DOWNLOAD] |
|
| 273. Ke Lin#, Wu Luo#, Na Yang, Lan Su, Hao Zhou, Xiang Hu, Yi Wang, Zia A. Khan, Weijian Huang, Gaojun Wu*, Guang Liang*. Inhibition of MyD88 attenuates Angiotensin II-induced hypertensive kidney disease via regulating renal inflammation. International Immunopharmacology,2022,112:109218. (二区，IF= 5.71）[PDF DOWNLOAD] |
|
| 271. Mengyang Wang, Wu Luo, Tianxiang Yu, Shiqi Liang, Chunpeng Zou, Jinfeng Sun, Gao Li*, Guang Liang*. Diacerein alleviates Ang II-induced cardiac inflammation and remodeling by inhibiting the MAPKs/c-Myc pathway. Phytomedicine,2022,106:154387. (一区，IF= 6.66）[PDF DOWNLOAD] |
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| 270. Xin Liu, Wu Luo, Jiahao Chen, Chenghong Hu, Rumbidzai N. Mutsinze, Xu Wang, Yanmei Zhang, Lijiang Huang, Wei Zuo, Guang Liang, Yi Wang*. USP25 deficiency exacerbates acute pancreatitis via upregulating TBK1-NF-κB signaling in macrophages. Cellular and Molecular Gastroenterology and Hepatology,2022,14:1103-22. (一区，IF= 8.8）[PDF DOWNLOAD] |
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| 269. Bin Yang#, Wu Luo#, Minxiu Wang, Yelin Tang, Weiwei Zhu, Leiming Jin, Meihong Wang, Yi Wang, Yi Zhang, Wei Zuo, Li-jiang Huang, Yunjie Zhao*, Guang Liang*. Macrophage-specific MyD88 deletion and pharmacological inhibition prevents liver damage in non-alcoholic fatty liver disease via reducing inflammatory response. BBA Molecular Basis of Disease,2022,1868:166480. (一区，IF= 6.63）[PDF DOWNLOAD] |
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| 268. Zheng Xu, Wu Luo, Lingfeng Chen, Zaishou Zhuang, Daona Yang, Jianchang Qian, Zia A. Khan, Xinfu Guan, Yi Wang, Xiaokun Li, Guang Liang*. Angiotensin II-induced FGFR1 activation in tubular epithelial cells promotes hypertensive kidney fibrosis and injury. Hypertension,2022,79:2028-41. (一区，IF= 9.90, Cover paper）[PDF DOWNLOAD] |
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| 266. Xi Chen#, Ying Zhao#, Xu Wang, Yimin Lin, Weixin Zhao, Di Wu, Jingye Pan, Wu Luo, Yi Wang, Guang Liang*. FAK mediates LPS-induced inflammatory lung injury through interacting TAK1 and activating TAK1-NFκB pathway. Cell Death & Disease,2022,13(7):589. (一区，IF= 9.69）[PDF DOWNLOAD] |
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| 265. Chengyi Dai, Wu Luo, Yanghao Chen, Siyuan Shen, Zhe Wang, Ruijie Chen, Jun Wang, Nipon Chattipakorn, Weijian Huang*, Guang Liang*. Tabersonine attenuates Angiotensin II-induced cardiac remodeling and dysfunction through targeting TAK1 and inhibiting TAK1-mediated cardiac inflammation. Phytomedicine,2022,103:154238. (一区，IF= 6.66）[PDF DOWNLOAD] |
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| 263. Mengyang Wang, Wu Luo, Tianxiang Yu, Shiqi Liang, Jinfeng Sun, Yi Zhang, Xue Han, Xiaohong Long, Guang Liang*, Gao Li*. Corynoline protects Ang II-induced hypertensive heart failure by increasing PPARα and inhibiting NF-κB pathway. Biomedicine & Pharmacotherapy,2022,150:113075. (二区，IF= 7.42）[PDF DOWNLOAD] |
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| 261. Mengyang Wang, Jinfeng Sun, Tianxiang Yu, Minxiu Wang, Leiming Jin, Shiqi Liang, Wu Luo, Yi Wang, Gao Li*, Guang Liang*. Diacerein protects liver against APAP-induced injury via targeting JNK and inhibiting JNK-mediated oxidative stress and apoptosis. Biomedicine & Pharmacotherapy,2022,149:112917. (二区，IF= 7.42）[PDF DOWNLOAD] |
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| 260. Wu Luo, Lin Ye, Xueting Hu, Meihong Wang, Minxiu Wang, Leiming Jin, Zhongxiang Xiao, Jianchang Qian, Yi Wang, Wei Zuo, Lijiang Huang, Guang Liang*. MD2 deficiency prevents high-fat diet-induced AMPK suppression and lipid accumulation through regulating TBK1 in non‐alcoholic fatty liver disease. Clinical and Translational Medicine,2022,12 (3):e777. (一区，IF= 8.55）[PDF DOWNLOAD] |
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| 259. Pengqin Chen#, Ying Zhao#, Jianqing Zhang, Yongli Duan, Jintian Dai, Jie He, Xiemin Wang, Xi Chen, Pan Chen, Weixin Zhao, Xu Wang, Zaishou Zhuang, Daona Yang , Guang Liang*, Qidong Tang *. Design, synthesis and anticancer evaluation of 6,7-disubstituted-4-phenoxyquinoline derivatives bearing 1,8-naphthyridine-3-carboxamide moiety as novel multi-target TKIs. Bioorganic Chemistry,2022,121:105672. (二区，IF= 5.30）[PDF DOWNLOAD] |
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| 258. QidongTang#, Ting Peng#, Jie Hu#, Tao Zhang#, Pengqin Chen, Daoxing Chen, Yunjie Wang, Lingfeng Chen, Linjiang Tong, Yi Chen, Hua Xie*, Guang Liang*. Discovery of N-(3-bromo-1H-indol-5-yl)-quinazolin-4-amine as an effective molecular skeleton to develop reversible/irreversible pan-HER inhibitors. European Journal of Medicinal Chemistry,2022,233:114249. (一区，IF= 7.08）[PDF DOWNLOAD] |
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| 257. Jianchang Qian*, Fei Zhuang, Yujing Chen, Xinrong Fan, Jun Wang, Zhe Wang, Yi Wang, Mingjiang Xu, Aleksandr V. Samorodov, Valentin N. Pavlov, Guang Liang*. Myeloid differential protein-2 inhibition improves diabetic cardiomyopathy via p38MAPK inhibition and AMPK pathway activation. BBA Molecular Basis of Disease,2022,1868:166369. (一区，IF= 6.63）[PDF DOWNLOAD] |
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| 251. Wu Luo, Libin Yang, Chenchen Qian, Bao Ma, Gloria M. Manjengwa, Xiaomin Miao, Jie Wang, Chenghong Hu, Bo Jin, Lingxi Zhang, Chao Zheng, Guang Liang, Yi Wang*. Flavokawain B alleviates LPS-induced acute lung injury via targeting myeloid differentiation factor 2. Acta Pharmacologica Sinica,2022,43:1758-1768. (一区，IF= 7.17）[PDF DOWNLOAD] |
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| 248. Qiuyan Zhang#, Sujing Xu#, Jianchang Qian#, Libin Yang, Pengqin Chen, Yi Wang, Xiang Hu, Yali Zhang, Wu Luo*, Guang Liang*. Pharmacological inhibition of MyD88 suppresses inflammation in tubular epithelial cells and prevents diabetic nephropathy in experimental mice. Acta Pharmacologica Sinica,2022,43:354-366. (一区，IF= 7.17）[PDF DOWNLOAD] |
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| 247. Yali Zhang#,*, Wenxin Zhang#, Jueqian Yan#, Yelin Tang, Wenjing Jia, Zhengwei Xu, Mingjiang Xu, Nipon Chattipakorn, Yi Wang, Jianpeng Feng, Zhiguo Liu*, Guang Liang*. Chalcone derivatives ameliorate lipopolysaccharide-induced acute lung injury and inflammation by targeting MD2. Acta Pharmacologica Sinica,2022,43:76-85. (一区，IF= 7.17）[PDF DOWNLOAD] |
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| 2021 |
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|---|
| 256. Jie Li, Jiaqi Yao, Lingfeng Chen, Dong Zou, Patrick J. Walsh*, Guang Liang*. Chemoselective acylation of N-acylglutarimides with N-acylpyrroles and aryl esters under transition-metal-free conditions. Organic Chemistry Frontiers,2021,8:6344–6349. (一区，IF=5.3）[PDF DOWNLOAD] |
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| 255. Lingfeng Chen*, Yanmei Zhang, Lina Yin, Binhao Cai, Ping Huang, Xiaokun Li, Guang Liang*. Fibroblast growth factor receptor fusions in cancer: opportunities and challenges. Journal of Experimental & Clinical Cancer Research,2021,40:345. (二区，IF= 11.16）[PDF DOWNLOAD] |
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| 254. Xiemin Wang#, Jun Yang#, Bingyu Ding, Pan Chen, Zhengwei Xu, Yunxi Zhao, Pengqin Chen, Nipon Chattipakorn, Guang Liang*, Di Wu*, Qidong Tang*. Design, synthesis and bioactivity evaluation of fisetin derivatives as potential anti-inflammatory agents against LPS-induced acute lung injury. Bioorganic & Medicinal Chemistry,2021,49:116456. (二区，IF= 3.64）[PDF DOWNLOAD] |
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| 253. Jianqing Zhang#, Hehua Xiong#, Feiyi Yang, Jie He, Ting Chen, Dongxue Fu, Pengwu Zheng, Qidong Tang*. Design, synthesis and biological evaluation of novel 4-(pyrrolo[2,3-d]pyrimidine-4-yloxy)benzamide derivatives as potential antitumor agents. Bioorganic & Medicinal Chemistry Letters,2021, 33:127740. (三区, IF=2.82）[PDF DOWNLOAD] |
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| 252. Jianqing Zhang#, Pengqin Chen#, Yongli Duan, Hehua Xiong, Hongmin Li, Yao Zeng, Guang Liang, Qidong Tang*, Di Wu*. Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d]pyrimidine derivatives containing 1,8-naphthyridine-4-one fragment. European Journal of Medicinal Chemistry,2021,215:113273. (一区，IF= 6.51）[PDF DOWNLOAD] |
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| 250. Libin Yang#, Wu Luo#, Qiuyan Zhang, Shanshan Hong, Yi Wang, Aleksandr V. Samorodov, Nipon Chattipakorn, Valentin N. Pavlov*, Guang Liang*. Cardamonin inhibits LPS-induced inflammatory responses and prevents acute lung injury by targeting myeloid differentiation factor 2. Phytomedicine,2021,93:153785. (一区，IF= 5,34）[PDF DOWNLOAD] |
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| 249. Lin Ye#, Xiaojun Chen#, Minxiu Wang, Leiming Jin, Zaishou Zhuang, Daona Yang, Xinfu Guan, Aleksandr V. Samorodov, Valentin N. Pavlov, Nipon Chattipakorn, Jianpeng Feng, Yi Wang, Wu Luo*, Guang Liang*. Curcumin Analogue C66 Attenuates Obesity-induced Myocardial Injury by Inhibiting JNK-mediated Inflammation. Biomedicine & Pharmacotherapy,2021,143:112121. (二区，IF= 6.53）[PDF DOWNLOAD] |
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| 246. Jianqiang Chen, Xiangxiang Jin, Yanan Mei, Zhe Shen, Jufan Zhu, Hongyi Shi, Minshan Wang, Xiaohui Zheng*, Guang Liang*. The different biological effects of TMPyP4 and cisplatin in the inflammatory microenvironment of osteosarcoma are attributed to G-quadruplex. Cell Proliferation,2021,54:e13101. (二区，IF= 6.83）[PDF DOWNLOAD] |
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| 245. Weixin Zhao, Yixiao Yan, Zhongxiang Xiao, Meihong Wang, Mingjiang Xu, Zhe Wang, Yi Wang, Zaishou Zhuang, Daona Yang, Gaozhi Chen*, Guang Liang*. Bicyclol Ameliorates Nonalcoholic Fatty Liver Disease in Mice via Inhibiting MAPKs and NF-κB Signaling Pathways. Biomedicine & Pharmacotherapy,2021,141:111874. (二区，IF= 6.53）[PDF DOWNLOAD] |
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| 244. Jianchang Qian#, Sihui Yin#, Lin Ye, Zhe Wang, Sheng Shu, Zhenxing Mou, Mingjiang Xu, Nipon Chattipakorn, Zhiguo Liu*, Guang Liang*. An indole-2-carboxamide derivative, LG4, alleviates diabetic kidney disease through inhibiting MAPK-mediated inflammatory responses. Journal of Inflammation Research,2021,14:1633-1645. (二区，IF= 6.92）[PDF DOWNLOAD] |
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| 243. Shushi Huang#, Wu Luo#, Gaojun Wu, Qirui Shen, Zaishou Zhuang, Daona Yang, Jinfu Qian, Xiang Hu, Yan Cai, Nipon Chattipakorn, Weijian Huang*, Guang Liang*. Inhibition of CDK9 attenuates atherosclerosis by inhibiting inflammation and phenotypic switching of vascular smooth muscle cells. Aging-US,2021, 13(11):14892-14909. (二区，IF= 5.68）[PDF DOWNLOAD] |
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| 242. Dezhong Wang#, Yuan Yin#, Shuyi Wang#, Tianyang Zhao#, Fanghua Gong, Yushuo Zhao, Beibei Wang, Yuli Huang, Zizhao Cheng, Guanghui Zhu, Zengshou Wang, Yang Wang, Jun Ren, Guang Liang*, Xiaokun Li*, Zhifeng Huang*. FGF1ΔHBS prevents diabetic cardiomyopathy by maintaining mitochondrial homeostasis and reducing oxidative stress via AMPK/Nur77 suppression. Signal Transduction and Targeted Therapy,2021,6(1):133. (一区，IF= 18.82）[PDF DOWNLOAD] |
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| 241. Shiju Ye# , Ke Lin#, Gaojun Wu, Ming-Jiang Xu, Peiren Shan, Weijian Huang*, Yi Wang*, Guang Liang*. Toll-like receptor 2 signaling deficiency in cardiac cells ameliorates Ang II-induced cardiac inflammation and remodeling. Translational Research,2021,233:62-76. (一区，IF= 7.01）[PDF DOWNLOAD] |
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| 240. Xiaojing Yang#, Wu Luo#, Li Li#, Xiang Hu, Mingjiang Xu, Yi Wang, Jianpeng Feng, Jianchang Qian, Xinfu Guan, Yunjie Zhao*, Guang Liang*. CDK9 inhibition improves diabetic nephropathy by reducing inflammation in the kidneys. Toxicology and Applied Pharmacology, 2021, 416:115465. (二区，IF= 4.21）[PDF DOWNLOAD] |
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239. Huaicheng Chen#, Tao Yan#, Zongming Song#, Shilong Ying, Beibei Wu, Xin Ju1, Xi Yang, Jia Qu, Wencan Wu, Zongduan Zhang, Yi Wang*. MD2 blockade prevents modified LDL-induced retinal injury in diabetes by suppressing NADPH oxidase-4 and its interaction with toll-like receptor-4. Experimental & Molecular Medicine, 2021, 53:681-694. (二区，IF= 8.72）[PDF DOWNLOAD]
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| 238. Lin Ye, Xueting Hu, Xiang Hu, Sihui Yin, Hanghui He, Shanshan Hong, Bin Yang, Krishna K. Singh, Jianpeng Feng, Yi Wang, Wu Luo*, Guang Liang*. Curcumin Analogue C66 Attenuates Obesity-induced Renal Injury by inhibiting Chronic Inflammation. Biomedicine & Pharmacotherapy, 2021, 137:111418. (二区，IF= 6.53）[PDF DOWNLOAD] |
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| 237. Jinfu Qian#, Wu Luo#, Chengyi Dai, Jun Wang, Xinfu Guan, Nipon Chattipakorn, Gaojun Wu, Weijian Huang*, Guang Liang*. Myeloid differentiation protein 2 mediates angiotensin II-induced inflammation and mesenchymal transition in vascular endothelium. BBA - Molecular Basis of Disease, 2021, 1867(3):166043. (一区，IF= 5.19）[PDF DOWNLOAD] |
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| 236. Wu Luo#, Xiaojun Chen#, Lin Ye#, Xuemei Chen#, Wenjing Jia, Yanni Zhao, Aleksandr V.Samorodov, Yali Zhang, Xueting Hu, Fei Zhuang, Jianchang Qian, Chao Zheng, Guang Liang*, Yi Wang*. Kaempferol attenuates streptozotocin-induced diabetic nephropathy by downregulating TRAF6 expression: the role of TRAF6 in diabetic nephropathy. Journal of Ethnopharmacology, 2021, 268:113553. (一区，IF= 4.36）[PDF DOWNLOAD] |
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| 235. Ke Lin, Wu Luo, Jueqian Yan, Siyuan Shen, Qirui Shen, Jun Wang, Xinfu Guan, Gaojun Wu, Weijian Huang*, Guang Liang*. TLR2 regulates angiotensin II-induced vascular remodeling and EndMT through NF-κB signaling. Aging-US, 2021, 13:2553-2574. (二区，IF= 5.68）[PDF DOWNLOAD] |
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| 234. Shushi Huang#, Shengban You#, Jinfu Qian, Chengyi Dai, Siyuan Shen, Jun Wang, Weijian Huang, Guang Liang*, Gaojun Wu*. Myeloid differentiation 2 deficiency attenuates AngII-induced arterial vascular oxidative stress,inflammation, and remodeling. Aging-US,2021,13:4409-4427. (二区，IF= 5.68）[PDF DOWNLOAD] |
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| 2020 |
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|---|
| 233. Li Li#, Chunyong Ding#, Chunpeng Zou, Zhi Xiong, Weiwei Zhu, Jianchang Qian, Mingjiang Xu, Ao Zhang*, Guang Liang*. A novel salviadione derivative, compound 15a, attenuates diabetes-induced renal injury by inhibiting NF-κB-mediated inflammatory responses. Toxicology and Applied Pharmacology, 2020, 409:115322. (二区，IF= 3.34）[PDF DONWLOAD] |
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| 232. Lingfeng Chen#，Lulu Zheng#，Pengqin Chen，Guang Liang*. Myeloid Differentiation Primary Response Protein 88 (MyD88): the central hub of TLR/IL-1R signaling. Journal of Medicinal Chemistry, 2020, 63(22):13316-13329. (一区，IF= 6.2）[PDF DONWLOAD] |
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| 231. Xi Chen, Ying Zhao, Wu Luo, Sian Chen, Feng Lin, Xi Zhang, Shijie Fan, Xian Shen, Yi Wang*, Guang Liang*. Celastrol induces ROS-mediated apoptosis via directly targeting peroxiredoxin-2 in gastric cancer cells. Theranostics, 2020, 10(22):10290-10308. (一区，IF= 8.58）[PDF DONWLOAD] |
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| 230. Xu Wang, Yi Wang, Victor Antony, Hongbin Sun*, Guang Liang*. Metabolism-Associated Molecular Patterns (MAMPs). Trends in Endocrinology and Metabolism, 2020, 31(10):712-724. (一区，IF= 11.64）[PDF DOWNLOAD] |
|
| 229. Xu Wang, Victor Antony, Yi Wang, Gaojun Wu, Guang Liang*. Pattern Recognition Receptor-mediated Inflammation in Diabetic Vascular Complications. Medicinal Research Reviews, 2020, 40(6):2466-2484. (一区，IF= 9.3）[PDF DOWNLOAD] |
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| 228. Yi Wang#,*, Wu Luo#, Jibo Han#, Zia A. Khan, Qilu Fang, Yiyi Jin, Xuemei Chen, Yali Zhang, Meihong Wang, Jianchang Qian, Weijian Huang, Hazel Lum, Gaojun Wu, Guang Liang*. MD2 activation by direct AGE interaction drives inflammatory diabetic cardiomyopathy. Nature Communications, 2020, 11(1):2148. (一区，IF= 12.0）[PDF DOWNLOAD] |
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| 227. Chengguang Zhao#, Lehe Yang#, Feng Zhou#, Yun Yu, Xiaojing Du, Youqun Xiang, Chenglong Li, Xiaoying Huang, Congying Xie, Zhiguo Liu, Jiayuh Lin, Liangxing Wang*, Guang Liang*, Ri Cui*. Feedback activation of EGFR is the main cause for STAT3 inhibition-irresponsiveness in pancreatic cancer cells. Oncogene, 2020, 39(20):3997-4013. (一区，IF= 6.6）[PDF DOWNLOAD] |
|
| 226. Shiju Ye#, Wu Luo#, Zia A. Khan#, Gaojun Wu, Lina Xuan, Peiren Shan, Ke Lin, Taiwei Chen, Jingying Wang, Xiang Hu, Shengjie Wang, Weijian Huang*, Guang Liang*. Celastrol Attenuates Angiotensin II-induced Cardiac Remodeling by Targeting STAT3. Circulation Research, 2020, 126(8):1007-1023. (一区，IF= 15.862）[PDF DOWNLOAD] |
|
| 225. Taiwei Chen#, Weijian Huang#, Jinfu Qian, Wu Luo, Peiren Shan, Yan Cai, Ke Lin, Gaojun Wu*, Guang Liang*. Macrophage-derived myeloid differentiation protein 2 plays an essential role in ox-LDL-induced inflammation and atherosclerosis. EBioMedicine,2020,53:102706. (一区，IF= 6.680）[PDF DOWNLOAD] |
|
| 224. Vinoyhkumar Rajamanickam#, Tao Yan#, Shanmei Xu#,Junguo Hui, Xiaohong Xu, Liuqing Ren, Zhoudi Liu, Guang Liang, Ouchen Wang, Yi Wang*. Selective targeting of the TLR4 co-receptor, MD2, prevents colon cancer growth and metastasis. International Journal of Biological Sciences,2020,16(8):1288-1302. (二区，IF= 4.067）[PDF DOWNLOAD] |
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| 223. Guang Liang#, Wei Meng#, Xiangjie Huang#, Wangyu Zhu, Changtian Yin, Canwei Wang, Matteo Fassan, Yun Yu, Masahisa Kudo, Sisi Xiao, Chengguang Zhao, Peng Zou, Yumin Wang, Xiaokun Li, Carlo M. Croce*, Ri Cui*. miR-196b-5p–mediated downregulation of TSPAN12 and GATA6 promotes tumor progression in non-small cell lung cancer. Proc Natl Acad Sci USA,2020,117(8):4347-4357. (一区，IF= 9.6）[PDF DOWNLOAD] |
|
| 222. Hui He#, Jie Guo#, Wei Sun, Bin Yang, Fengzhi Zhang*, Guang Liang*. Palladium-Catalyzed Direct Mono- or Polyhalogenation of Benzothiadiazole Derivat. Journal of Organic Chemistry,2020,85(5):3788-3798. (二区，IF= 4.75）[PDF DOWNLOAD] |
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221. Lingfeng Chen, William M. Marsiglia, Huaibin Chen, Joseph Katigbak, Hediye Erdjument-Bromage, David J. Kemble, Lili Fu, Jinghong Ma, Gongqin Sun, Yingkai Zhang, Guang Liang, Thomas A. Neubert, Xiaokun Li, Nathaniel J. Traaseth* & Moosa Mohammadi*. Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation. Nature Chemical Biology,2020,16(3):267-277. (一区，IF= 12.154）[PDF DOWNLOAD]
|
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| 220. Yali Zhang#, Hongjin Chen#, Wenxin Zhang#, Yan Cai, Peiren Shan, Di Wu, Bing Zhang, Hui Liu, Zia Khan, Guang Liang*. Arachidonic acid inhibits inflammatory responses by binding to myeloid differentiation factor-2 (MD2) and preventing MD2/toll-like receptor 4 signaling activation. BBA - Molecular Basis of Disease,2020,1866(5):165683. (一区，IF= 4.328）[PDF DOWNLOAD] |
|
| 219. Zengqiang Song#,*, Chaochao Ding#, Shaoli Wang#, Qian Dai, Yaoguang Sheng, Zhilong Zheng, Guang Liang*. Metal-Free Regioselective C–H Chalcogenylation of Coumarins/ (Hetero)Arenes at Ambient Temperature. Chemical Communications, 2020, 56:1847-1850. (一区，IF= 6.164）[PDF DOWNLOAD] |
|
| 218. Gaozhi Chen, Yuyan Bao, Qiaoyou Weng, Yingxin Zhao, Xiaoyao Lu, Lili Fu, Lingfeng Chen, Zhiguo Liu, Xiaomin Zhang and Guang Liang*. Compound 15c, a Novel Dual Inhibitor of EGFRL858R/T790M and FGFR1, Efficiently Overcomes Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Resistance of Non-Small-Cell Lung Cancers. Frontiers in Pharmacology,2020,10:1533. (二区，IF= 3.845）[PDF DOWNLOAD] |
|
| 217. Ziheng Zhang#, Renyu Lin,#, Zhoudi Liu, Tao Yan, Yiqun Xia, Leping Zhao, Feng Lin, Xi Zhang, Chenglong Li, Yi Wang* . Curcumin analog, WZ37, promotes G2/M arrest and apoptosis of HNSCC cells through Akt/mTOR inhibition. Toxicology in Vitro, 2020, 104754. (三区，IF= 3.067）[PDF DOWNLOAD] |
|
| 216. Vinothkumar Rajamanickam#, Tao Yan#, Liangrong Wu, Yanni Zhao, Xiaohong Xu, Heping Zhu, Xi Chen, Meihong Wang, Zhoudi Liu, Zhiguo Liu, Guang Liang, Yi Wang*. Allylated curcumin analog CA6 inhibits TrxR1 and leads to ROS-dependent apoptotic cell death in gastric cancer through Akt-FoxO3a. Cancer Management and Research, 2020, 12:247-263. (三区，IF= 2.243）[PDF DOWNLOAD] |
|
| 2019 |
|
|---|
| 215. Qianqian Zhang, Weiqian Chen, Xiuling Lv, Qiaoyou Weng, Minjiang Chen, Ri Cui, Guang Liang*, Jiansong Ji*. Piperlongumine, a Novel TrxR1 Inhibitor, Induces Apoptosis in Hepatocellular Carcinoma Cells by ROS-Mediated ER Stress. Frontiers in Pharmacology, 2019, 10(11):848-848. (二区，IF= 3.845）[PDF DOWNLOAD] |
|
| 214. Lihua Wang#, Canwei Wang#, Zheying Tao#, Liqian Zhao#, Zheng Zhu, Wencan Wu, Ye He, Hong Chen, Bin Zheng, Xiangjie Huang, Yun Yu, Linjun Yang, Guang Liang*, Ri Cui* and Tongke Chen*. Curcumin derivative WZ35 inhibits tumor cell growth via ROS-YAP-JNK signaling pathway in breast cancer. Journal of Experimental & Clinical Cancer Research,2019,38(1)：460. (二区，IF= 5.646）[PDF DOWNLOAD] |
|
| 213. Chao Zheng#, Lan Huang#, Wu Luo, Weihui Yu, Xueting Hu, Xinfu Guan, Yan Cai, Chunpeng Zou, Haimin Yin, Zheng Xu, Guang Liang*, Yi Wang*. Inhibition of STAT3 in tubular epithelial cells prevents kidney fibrosis and nephropathy in STZ-induced diabetic mice. Cell Death & Disease,2019,10(11)：848-848. (二区，IF= 5.959）[PDF DOWNLOAD] |
|
| 212. Chaochao Ding, Shaoli Wang, Yaoguang Sheng, Qian Dai, Yunjie Zhao,* Guang Liang* and Zengqiang Song*. One-step construction of unsymmetrical thioureas and oxazolidinethiones from amines and carbon disulfide via a cascade reaction sequence. RSC Advances,2019,9(46)：26768-26772. (三区，IF= 3.049）[PDF DOWNLOAD] |
|
| 211. Xiaohong Xu, Vinothkumar Rajamanickam, Sheng Shu, Zhoudi Liu, Tao Yan, Jinxin He, Zhiguo Liu, Guilong Guo, Guang Liang, Yi Wang*. Indole-2-carboxamide derivative LG25 inhibits triple-negative breast cancer growth by suppressing Akt/mTOR/NF-κB signalling pathway. Drug Design, Development and Therapy, 2019, 13：3539-3550. (三区，IF= 3.208）[PDF DOWNLOAD] |
|
| 210. Chun Lu#, Bing Zhang#, Tingting Xu, Wenxin Zhang, Bin Bai, Zhongxiang Xiao, Liqin Wu, Guang Liang, Yali Zhang* , Yuanrong Dai*. Piperlongumine reduces ovalbumin-induced asthma and airway inflammation by regulating NF-κB activation. International Journal of Molecular Medicine, 2019, 44:1855-1865. (三区，IF= 2.928）[PDF DOWNLOAD] |
|
| 209. Hongjin Chen#, Yali Zhang#, Wenxin Zhang#, Hui Liu, Chuchu Sun, Bing Zhang, Bin Bai, Di Wu, Zhongxiang Xiao, Hazel Lum, Jianmin Zhou, Ruijie Chen*, Guang Liang*. Inhibition of myeloid differentiation factor 2 by baicalein protects against acute lung injury. Phytomedicine, 2019, 63:152997. (一区，IF= 3.61）[PDF DOWNLOAD] |
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| 208. Wu Luo#, Lan Huang#, Jingying Wang, Fei Zhuang, Zheng Xu, Haimin Yin, Yuanyuan Qian, Guang Liang, Chao Zheng*, Yi Wang*. Inhibition of EGFR-STAT3 attenuates cardiomyopathy in streptozotocin-induced type 1 diabetes. Journal of Endocrinology, 2019, 242(3):199-210. (二区，IF= 4.01）[PDF DOWNLOAD] |
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| 207. Shengban You#, Jianchang Qian#, Gaojun Wu#, Yuanyuan Qian, Zhengxian Wang, Taiwei Chen, Jingying Wang, Weijian Huang*, Guang Liang*. Schizandrin B attenuates angiotensin II induced Endothelial to Mesenchymal Transition in vascular endothelium by suppressing NF-κB activation. Phytomedicine, 2019, 62:152955. (一区，IF= 3.61）[PDF DOWNLOAD] |
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| 206. Xiaohong Xu, Rajamanicham Vinothakumar, Sujing Xu, Zhoudi Liu, Tao Yan, Guang Liang, Guilong Guo, Huiping Zhou*, Yi Wang*. Schisandrin A inhibits triple negative breast cancer cells by regulating Wnt/ER stress signaling pathway. Biomedicine & Pharmacotherapy, 2019, 115:108922. (三区，IF= 3.39）[PDF DOWNLOAD] |
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| 205. Sujing Xu#, Wu Luo#, Xiaohong Xu, Yuanyuan Qian, Zheng Xu, Weihui Yu, Xiaoou Shan, Xinfu Guan, Hazel Lum, Huiping Zhou*, Yi Wang*. MD2 blockade prevents oxLDL-induced renal epithelial cell injury and protects against high fat diet-induced kidney dysfunction. Journal of Nutritional Biochemistry, 2019, 70:47-55. (二区，IF= 4.414）[PDF DOWNLOAD] |
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| 204. Zhiguo Liu,#,* Lingfeng Chen#, Pengtian Yu, Yali Zhang, Bo Fang, Chao Wu, Wu Luo, Xianxin Chen, Chenglong Li, Guang Liang*. Discovery of 3-(indol-5-yl)-indazole derivatives as novel myeloid differentiation protein 2/toll-like receptor 4 antagonists for treatment of acute lung injury. Journal of Medicinal Chemistry, 2019, 62(11):5453-5469. (Cover story)(一区，IF= 6.23）[PDF DOWNLOAD] |
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| 203. Chunyong Ding#, Hongjin Chen#; Bing Liang, Mingkun Jiao, Guang Liang*, Ao Zhang*. Biomimetic Synthesis of Natural Product Salviadione and Its Hybrids: Discovery of Tissue-Specific Anti-Inflammatory Agents for Acute Lung Injury. Chemical Science, 2019, 10:4667-4672. (一区，IF= 9.06）[PDF DOWNLOAD] |
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| 202. Yi Wang#,*, Qilu Fang#, Yiyi Jin#, Zhoudi Liu, Chunpeng Zou, Weihui Yu, Weixin Li, Xiaoou Shan, Ruijie Chen, Zia Khan, Guang Liang*. Blockade of myeloid differentiation 2 attenuates diabetic nephropathy by reducing activation of the renin-angiotensin system in mouse kidneys. British Journal of Pharmacology, 2019, 176:2642–2657. (一区，IF= 6.81）[PDF DOWNLOAD] |
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| 201. Zheng Xu#, Chunpeng Zou#, Weihui Yu, Sujing Xu, Lan Huang, Zia Khan, Jingying Wang, Guang Liang*, Yi Wang*. Inhibition of STAT3 activation mediated by toll‐like receptor 4 attenuates angiotensin II‐induced renal fibrosis and dysfunction. British Journal of Pharmacology, 2019, 176:2627–2641. (一区，IF= 6.81）[PDF DOWNLOAD] |
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| 200. Bo Fang#， Zhongxiang Xiao#， Yinda Qiu#， Sheng Shu, Xianxin Chen, Xiaojing Chen, Fei Zhuang, Yunjie Zhao*, Guang Liang*, Zhiguo Liu*. Synthesis and Anti-inflammatory Evaluation of (R)-, (S)- and (±)-Sanjuanolide Isolated from Dalea frutescens. J Nat Prod, 2019, 82(4):748-755. (二区，IF= 3.885）[PDF DOWNLOAD] |
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| 199. Taiwei Chen# , Wu Luo#, Gaojun Wu, Lanlan Wu, Shushi Huang, Jieli Li, Jingying Wang, Xiang Hu, Weijian Huang*, Guang Liang*. A novel MyD88 inhibitor LM9 prevents atherosclerosis by regulating inflammatory responses and oxidative stress in macrophages. Toxicology and Applied Pharmacology, 2019, 370:44-55. (二区，IF= 3.616）[PDF DOWNLOAD] |
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| 198. Zengqiang Song*,#, Yan Zhou#, Wenxin Zhang#, Lingling Zhan, Yuanzu Yu, Yuehui Chen, Wenjing Jia, Zhiguo Liu, Jianchang Qian, Yali Zhang, Chenglong Li, Guang Liang*. Base Promoted Synthesis of Novel Indole-Dithiocarbamate Compounds as Potential Anti-Inflammatory Therapeutic Agents for Treatment of Acute Lung Injury. Eur J Med Chem, 2019, 171:54-65. (一区，IF= 4.816）[PDF DOWNLOAD] |
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| 197. Wu Luo#, Yiyi Jin#, Gaojun Wu, Weiwei Zhu, Yuanyuan Qian, Yali Zhang, Jieli Li, Aisong Zhu, Guang Liang*. Blockage of ROS and MAPKs-mediated inflammation via restoring SIRT1 by a new compound LF10 prevents type 1 diabetic cardiomyopathy. Toxicology and Applied Pharmacology, 2019, 370:24-35. (二区，IF= 3.616）[PDF DOWNLOAD] |
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| 196. Jianchang Qian#, Xianxin Chen#, Sheng Shu#, Wenxin Zhang, Bo Fang, Xiaojing Chen, Yunjie Zhao*, Zhiguo Liu*, Guang Liang. Design and synthesis novel di-carbonyl analogs of curcumin (DACs) act as potent anti-inflammatory agents against LPS-induced acute lung injury (ALI). Eur J Med Chem, 2019, 167:414-425. (一区，IF= 4.816）[PDF DOWNLOAD] |
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| 195. Yunjie Zhao#, Yongkai Cao#, Huizhen Chen#, Fei Zhuang, Chao Wu, Goo Yoon, Weiwei Zhu, Ying Su, Suqing Zheng, Zhiguo Liu*, Seung Hoon Cheon*. Synthesis, biological evaluation, and molecular docking study of novel allyl-retrochalcones as a new class of protein tyrosine phosphatase 1B inhibitors. Bioorg Med Chem, 2019, 27:963-977. (三区，IF= 2.881）[PDF DOWNLOAD] |
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| 194. Jianchang Qian#, Xuemei Chen#, Xiaojun Chen#, Chuchu Sun, Yuchen Jiang, Yuanyuan Qian, Yali Zhang, Zia Khan, Jianmin Zhou*, Guang Liang*, Chao Zheng*. Kaempferol reduces K63-linked polyubiquitination to inhibit nuclear factor-κB and inflammatory responses in acute lung injury in mice. Toxicology Letters, 2019, 306:53-60. (二区，IF= 3.17）[PDF DOWNLOAD] |
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| 193. Xin Ju, Xi Yang, Tao Yan, Huaicheng Chen, Zongming Song, Zongduan Zhang, Wencan Wu*, Yi Wang*. EGFR inhibitor, AG1478, inhibits inflammatory infiltration and angiogenesis in mice with diabetic retinopathy. Clin Exp Pharmacol Physiol, 2019, 46:75-85. (四区，IF= 2.092）[PDF DOWNLOAD] |
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| 192. Li Li#, Wu Luo#, Yuanyuan Qian#, Weiwei Zhu, Jianchang Qian, Jieli Li, Yiyi Jin, Xuzhong Xu*, Guang Liang*. Luteolin protects against diabetic cardiomyopathy by inhibiting NF-κB-mediated inflammation and activating the Nrf2-mediated antioxidant responses. Phytomedicine, 2019, 59:152774. (一区，IF= 3.6）[PDF DOWNLOAD] |
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| 191. Xi Chen, Xiaoming Chen, Xi Zhang, Li Wang, Peihai Cao, Vinothkumar Rajamanickam, Chao Wu, Huiping Zhou, Yuepiao Cai, Guang Liang*, Yi Wang*. Curcuminoid B63 induces ROS-mediated paraptosis-like cell death by targeting TrxR1 in gastric cells. Redox Biology, 2019, 21:101061. (二区，IF= 7.13）[PDF DOWNLOAD] |
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| 190. Lingfeng Chen#, Hongjin Chen#, Pengqin Chen#, Wenxin Zhang, Chao Wu, Chuchu Sun, Wu Luo, Lulu Zheng, Zhiguo Liu, Guang Liang*. Development of 2-amino-4-phenylthiazole analogues to disrupt myeloid differentiation factor 88 and prevent inflammatory responses in acute lung injury. Eur J Med Chem, 2019, 161:22-38. (一区，IF= 4.816）[PDF DOWNLOAD] |
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| 189. Beibei Wu#, Zhongxiang Xiao#, Wenxin Zhang#, Hongjin Chen, Hui Liu, Jialing Pan, Xiaohong Cai, Guang Liang, Bin Zhou*, Xiaoou Shan*, Yali Zhang*. A novel resveratrol-curcumin hybrid, a19, attenuates high fat diet-induced nonalcoholic fatty liver disease. Biomedicine & Pharmacotherapy, 2019, 110: 951-960. (三区，IF= 3.457）[PDF DOWNLOAD] |
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| 188. Wenxin Zhang, Hongjin Chen, Chuchu Sun, Beibei Wu, Bin Bai, Hui Liu, Xiaoou Shan, Guang Liang, Yali Zhang*. A novel resveratrol analog PA19 attenuates obesity-induced cardiac and renal injury by inhibiting inflammation and inflammatory cell infiltration. Mol Med Rep, 2019, 19:4770-4778. (四区，IF= 1.912）[PDF DOWNLOAD] |
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| 2018 |
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|---|
| 187. Xuanxuan Dai# Changtian Yin#, Yi Zhang, Guilong Guo, Chengguang Zhao, Ouchen Wang, Youqun Xiang, Xiaohua Zhang*, Guang Liang*. Osthole inhibits triple negative breast cancer cells by suppressing STAT3. Journal of Experimental & Clinical Cancer Research, 2018, 37(1):322. (二区，IF= 6.22）[PDF DOWNLOAD] |
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| 186. Chaochao Ding, Yuanzu Yu, Qiongli Yu, Zixin Xie, Yan Zhou, Jianmin Zhou*, Guang Liang*, Zengqiang Song*. NIS/TBHP induced regioselective selenation of (hetero) arenes via direct C-H functionalization. ChemCatChem, 2018, 10:1-6. (二区，IF= 4.674）[PDF DOWNLOAD] |
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| 185. Yuanzu Yu#, Yan Zhou#, Zengqiang Song*, Guang Liang. An efficient t-BuOK promoted C3-chalcogenylation of indoles with dichalcogenides. Org Biomol Chem, 2018, 16:4958-4962. (二区，IF= 3.423）[PDF DOWNLOAD] |
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| 184. Qinqin Xia#, Xiaodong Bao#, Chuchu Sun#, Di Wu, Xiaona Rong, Zhiguo Liu, Yugui Gu, Jianmin Zhou, Guang Liang*. Design, synthesis and biological evaluation of novel 2-sulfonylindoles as potential anti-inflammatory therapeutic agents for treatment of acute lung injury. Eur J Med Chem, 2018, 160:120-132. (一区，IF= 4.816）[PDF DOWNLOAD] |
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| 183. Jibo Han#, Shiju Ye#, Chunpeng Zou, Taiwei Chen, Jingying Wang, Jieli Li, Liqin Jiang, Jianjiang Xu, Weijian Huang*, Yi Wang*, Guang Liang*. Angiotensin II causes biphasic STAT3 activation through TLR4 to initiate cardiac remodeling. Hypertension, 2018, 72:1301-1311. (一区，IF= 6.823）[PDF DOWNLOAD] |
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| 182. Xuanxuan Dai#, Changtian Yin#, Guilong Guo, Yi Zhang, Chenguang Zhao, Jianchang Qian, Ouchen Wang, Xiaohua Zhang*, Guang Liang*. Schisandrin B exhibits potent anticancer activity in triple negative breast cancer by inhibiting STAT3. Toxicology and Applied Pharmacology, 2018, 358:110-119. (二区，IF= 3.616）[PDF DOWNLOAD] |
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| 181. Zhen Wang#, Yali Zhang#, Daniel M. Pinkas#, Alice E. Fox, Jinfeng Luo, Huocong Huang, Shengyang Cui, Qiuping Xiang, Tingting Xu, Qiuju Xun, Dongsheng Zhu, Zhengchao Tu, Xiaomei Ren, Rolf A. Brekken, Alex N. Bullock, Guang Liang*, Ke Ding*, and Xiaoyun Lu*. Design, Synthesis, and Biological Evaluation of 3-(Imidazo[1,2-a]pyrazin-3-ylethynyl)-4-isopropyl-N-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)phenyl)benzamide as a Dual Inhibitor of Discoidin Domain Receptors 1 and 2. J Med Chem, 2018, 61(17):7977-7990. (一区，IF= 6.253）[PDF DOWNLOAD] |
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| 180. Xuanxuan Dai#, Junru Zhang#, Guilong Guo, Yuepiao Cai, Ri Cui, Changtian Yin, Weidong Liu, Rajamanickam Vinothkumar, Tingting Zhang, Guang Liang*, Xiaohua Zhang*. A mono-carbonyl analog of curcumin induces apoptosis in drug-resistant EGFR-mutant lung cancer through the generation of oxidative stress and mitochondrial dysfunction. Cancer Management and Research, 2018, 10:3069-3082. (二区，IF= 3.702）[PDF DOWNLOAD] |
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| 179. Xiaodong Bao, Xiaona Rong, Zhiguo Liu, Yugui Gu, Guang Liang*, Qinqin Xia*. Potassium tert-Butoxide-Mediated Metal-Free Synthesis of Sulfonamides from Sodium Sulfinates and N,N-Disubstituted Formamides. Tetrahedron Letters,2018,59:2853-2858. (三区，IF= 2.125）[PDF DOWNLOAD] |
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| 178. Yiyi Jin#, Jianchang Qian#, Xin Ju, Xiaodong Bao, Li Li, Suqing Zheng, Xiong Chen, Zhongxiang Xiao, Xuemei Chen, Weiwei Zhu, Weixin Li, Wencan Wu*, Guang Liang*. Osthole protects against acute lung injury by suppressing NF-κB-dependent inflammation.Mediators of Inflammation,2018,4934592. (三区，IF= 3.549）[PDF DOWNLOAD] |
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| 177. Xiaoping Yang*, Shiqing Wang, Yali Zhang, Guang Liang*, Ting Zhu, Lijie Zhang, Shaoming Huang*, Desmond Schipper and Richard A. Jones*. A self-assembling luminescent lanthanide molecular nanoparticle with potential for live cell imaging.Chemical Science,2018,9:4630-4637. (一区，IF= 9.063）[PDF DOWNLOAD] |
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| 176. Jiansong Ji#, Weiqian Chen#, Weishuai Lian, Ruijie Chen, Jinqing Yang, Qianqian Zhang, Qiaoyou Weng, Zia Khan, Jie Hu, Xi Chen, Peng Zou, Xiaoming Chen*, Guang Liang*. (S)-Crizotinib Reduces Gastric Cancer Growth Through Oxidative DNA Damage and Triggers Pro-survival Akt Signal. Cell Death and Disease, 2018, 9(6):660. (二区，IF= 5.638）[PDF DOWNLOAD] |
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| 175. Siyang Xiao#, Wenxin Zhang#, Hongjin Chen, Bo Fang, Yinda Qiu, Xianxin Chen, Lingfeng Chen, Sheng Shu, Yunjie Zhao*, Zhiguo Liu*, Guang Liang. Design, synthesis, and structure–activity relationships of 2-benzylidene-1-indanone derivatives as anti-inflammatory agents for treatment of acute lung injury. Drug Design, Development and Therapy,2018,12: 887-899. (三区，IF= 2.935）[PDF DOWNLOAD] |
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| 174. Yali Zhang#, Zhiguo Liu#, Jianzhang Wu, Bin Bai, Hongjin Chen, Zhongxiang Xiao, Lingfeng Chen, Yunjie Zhao, Hazel Lum, Yi Wang, Hong Zhang*, Guang Liang*. New MD2 inhibitors derived from curcumin with improved anti-inflammatory activity.Eur. J Med. Chem,2018,148: 291-305. (一区，IF= 4.816）[PDF DOWNLOAD] |
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| 173. Xuemei Chen#, Jianchang Qian#, Lintao Wang, Jieli Li, Yunjie Zhao, Jibo Han, Zia Khan, Xiaojun Chen, Jingying Wang*, Guang Liang*. Kaempferol attenuates hyperglycemia-induced cardiac injuries by inhibiting inflammatory responses and oxidative stress.Endocrine,2018,60(1): 83-94. (二区，IF= 3.179）[PDF DOWNLOAD] |
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| 172. Gaozhi Chen#, Yang Liu#, Regina Goetz, Lili Fu, Seetharaman Jayaraman, Ming-Chang Hu, Orson W. Moe, Guang Liang, Xiaokun Li*, Moosa Mohammadi*. α-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling.Nature,2018,553(7689): 461-466. (一区，IF= 41.577)[PDF DOWNLOAD] |
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| 171. Lingfeng Chen, Weitao Fu,Lulu Zheng, Yi Wang*, Guang Liang*. Recent Progress in the Discovery of Myeloid Differentiation 2 (MD-2) Modulators for Inflammatory Diseases.Drug Discovery Today,2018,23(6):1187-1202. (一区，IF= 6.848）[PDF DOWNLOAD] |
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| 170. Xiong Chen#, Weihui Yu#, Weixin Li#, Hailing Zhang, Weijian Huang, Jingying Wang, Weiwei Zhu, Qilu Fang, Chao Chen, Xiaokun Li*, Guang Liang*. An Anti-inflammatory Chalcone Derivative Prevents Heart and Kidney From Hyperlipidemia-induced Injuries by Attenuating Inflammation.Toxicology and Applied Pharmacology,2018,338: 43-53. (二区，IF= 3.616）[PDF DOWNLOAD] |
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| 169. Huaicheng Chen#, Zongming Song#, Shilong Ying, Xi Yang, Wei Wu, Qiufan Tan, Xin Ju, Wencan Wu, Xin Zhang, Jia Qu*, Yi Wang*. Myeloid differentiation protein 2 induced retinal ischemia reperfusion injury via upregulation of ROS through a TLR4-NOX4 pathway.Toxicology Letters,2018,282: 109-120. (二区，IF= 3.166）[ PDF DOWNLOAD] |
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| 168. Dandan Liang#, Hongjin Chen#, Leping Zhao#, Wenxin Zhang#, Jie Hu, Zhiguo Liu, Peng Zhong, Wei Wang, Jingying Wang, Guang Liang*. Inhibition of EGFR attenuates fibrosis and stellate cell activation in diet-induced model of nonalcoholic fatty liver disease.BBA - Molecular Basis of Disease,2018,1864(1):133-142. (二区，IF= 5.108）[PDF DOWNLOAD] |
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| 167. Weishan Zhuge, Ruijie Chen, Vladimir Katanaev, Xidan Dong, Khan Zia, Xiangwei Sun, Xuanxuan Dai, Miao Bao, Xian Shen*, Guang Liang*. Costunolide specifically binds and inhibits thioredoxin reductase 1 to induce apoptosis in colon cancer.Cancer Letters,2018,412:46-58. (二区，IF= 6.491）[PDF DOWNLOAD] |
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| 166. Qilu Fang#, Jingying Wang#, Yali Zhang#, Lintao Wang#, Weixin Li#, Jibo Han, Weijian Huang, Guang Liang*, Yi Wang*. Inhibition of myeloid differentiation factor-2 attenuates obesity-induced cardiomyopathy and fibrosis.BBA - Molecular Basis of Disease,2018,1864(1): 252-262. (二区，IF= 5.108）[PDF DOWNLOAD] |
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| 165. Yali Zhang#, Tingting Xu#, Zheer Pan#, Xiangting Ge, Chuchu Sun, Chun Lu, Hongjin Chen, Zhongxiang Xiao, Bing Zhang*, Yuanrong Dai*, Guang Liang*. Shikonin inhibits myeloid differentiation protein 2 to prevent LPS‐induced acute lung injury.British Journal of Pharmacology,2018,175(5): 840-854. (一区，IF= 6.81）[PDF DOWNLOAD] |
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| 164. Shengban You#, Jianchang Qian#, Chuchu Sun#, Hailing Zhang, Shiju Ye, Taiwei Chen, Zheng Xu, Jingying Wang, Weijian Huang*, Guang Liang*. An Aza resveratrol-chalcone derivative 6b protects mice against diabetic cardiomyopathy by alleviating inflammation and oxidative stress. J Cell Mol Med, 2018, 22(3): 1931-1943. (二区，IF= 4.302）[PDF DOWNLOAD] |
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| 163. Lili Huang#, Jiabing Wang#, Liping Chen#, Min Zhu#, Shoubiao Wu, Shenghui Chu, Yuantie Zheng, Ziliang Fan, Jiafeng Zhang, Wulan Li, Dahui Chen, Xiufei Yang, Sicen Wang, Peihong Qiu*, Jianzhang Wu*. Design, Synthesis, and Evaluation of NDGA Analogues as Potential Anti-Ischemic Stroke Agent. Eur. J Med. Chem, 2018, 143: 1165-1173. (二区，IF= 4.816）[PDF DOWNLOAD] |
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| 162. Lingfeng Chen, Weitao Fu, Lulu Zheng, Zhiguo Liu, Guang Liang*. Recent progress of small-molecule epidermal growth factor receptor (EGFR) inhibitors against C797S resistance in non-small-cell lung cancer. Journal of Medicinal Chemistry, 2018, 61(10):4290-4300. (一区，IF= 6.253）[PDF DOWNLOAD] |
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| 161. Yali Zhang#, Beibei Wu#, Hailing Zhang, Xiangting Ge, Shilong Ying, Mengwei Hu, Weixin Li, Yi Huang, Li Wang, Chao Chen, Xiaoou Shan*, Guang Liang*. Inhibition of MD2-dependent inflammation attenuates the progression of non-alcoholic fatty liver disease. Journal of Cellular and Molecular Medicine, 2018, 22(2): 936-947. (二区，IF= 4.302)[PDF DOWNLOAD] |
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| 160. Guang Liang#, Lintao Song#, Zilu Chen#, Yuanyuan Qian, Junjun Xie, Longwei Zhao, Qian Lin, Guanghui Zhu, Yi Tan, Xiaokun Li*, Moosa Mohammadi*, Zhifeng Huang*. Fibroblast Growth Factor 1 Ameliorates Diabetic Nephropathy Through an Anti-inflammatory Mechanism. Kidney International, 2018, 93: 95-109. (一区，IF= 8.429)[PDF DOWNLOAD] |
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| 159. Lei Wang, Huaicheng Chen, Xi Yang, Jianjian Tao, Guang Liang, Jianzhang Wu, Wencan Wu, Yi Wang, Zongming Song*, Xin Zhang*. The novel chalcone analogue, L2H17, protects retinal ganglionic cells from oxidative stress-induced apoptosis. Neural Regeneration Research, 2018, 13(9):1665-1672. (四区，IF= 2.234)[PDF DOWNLOAD] |
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| 158. Lingfeng Chen#, Yiyi Jin#, Hongjin Chen#, Chuchu Sun#, Weitao Fu, Lulu Zheng, Min Lu, Pengqin Chen, Gaozhi Chen, Yali Zhang, Zhiguo Liu, Yi Wang, Zengqiang Song*, Guang Liang*. Discovery of caffeic acid phenethyl ester derivatives as novel myeloid differentiation protein 2 inhibitors for treatment of acute lung injury. Eur. J Med. Chem, 2018, 143: 361-375. (一区，IF= 4.816）[PDF DOWNLOAD] |
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| 2017 |
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| 157. Chunpeng Zou#, Weixin Li#, Yong Pan#, Zia A. Khan, Jieli Li, Xixi Wu, Yi Wang, Liancheng Deng, Guang Liang*, Yunjie Zhao*. 11β-HSD1 inhibition ameliorates diabetes-induced cardiomyocyte hypertrophy and cardiac fibrosis through modulation of EGFR activity. Oncotarget, 2017, 8(56): 96263-96275. (一区，IF= 5.2）[PDF DOWNLOAD] |
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| 156. Vinothkumar Rajamanickam, Heping Zhu, Chen Feng, Xi Chen, Hailun Zheng, Xiaohong Xu, Qianqian Zhang, Peng Zou, Guodong He, Xuanxuan Dai, Xi Yang, Yi Wang, Zhiguo Liu, Guang Liang*, Guilong Guo*. Novel allylated monocarbonyl analogs of curcumin induce mitotic arrest and apoptosis by reactive oxygen species-mediated endoplasmic reticulum stress and inhibition of STAT3. Oncotarget, 2017, 8(60): 101112-101129. (一区，IF= 5.2)[PDF DOWNLOAD] |
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| 155. Jian Chen#, Linlin Zhang#, Yilai Shu, Liping Chen, Min Zhu, Song Yao, Jiabing Wang, Jianzhang Wu, Guang Liang, Haitao Wu*, Wulan Li*. Curcumin Analogue CA15 Exhibits Anticancer Effects on HEp-2 Cells via Targeting NF-κB. BioMed Research International, 2017, 2017：4751260. (三区，IF= 2.476）[PDF DOWNLOAD] |
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| 154. Shilong Ying#, Jiabib Wang#, Chaochao Xu#, Yanting Kang, Xiaoqin Zhang, Lingyi Shi, Lei Fan, Zhankun Wang, Jiabei Zhou, Xiaoping Wu, Jianzhang Wu*, Wulan Li*, and Guang Liang. Design, Synthesis, and Antiproliferative Activity Assessment of Non-ATP-Competitive Fibroblast Growth Factor Receptor1 Inhibitors. Russ. J. Gen. Chem, 2017, 86(12): 2744-2751. (四区，IF=0.481)[PDF DOWNLOAD] |
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| 153. Jianzhang Wu#, Jiye Ren#, Song Yao#, Jiabing Wang#, Lili Huang, Peng Zhou, Di yun, Qing Xu, Shoubiao Wu*, Zhankun Wang*, Peihong Qiu*. Novel antioxidant’ synthesis and their anti-oxidative activity through activating Nrf2 signaling pathway. Bioorgan Med Chem.Letters, 2017, 27(7): 1616-1619. (三区, IF=2.9)[PDF DOWNLOAD] |
|
| 152. Peihong Qiu#, Shanshan Zhang#, Yangyang Zhou#, Min Zhu#, Yanting Kang#, Dahui Chen, Jiabing Wang, Peng Zhou, Wulan Li, Qing Xu, Rong Jin*, Jianzhang Wu*, Guang Liang. Synthesis and evaluation of asymmetric curcuminoid analogs as potential anticancer agents that downregulate NF-κB activation and enhance the sensitivity of gastric cancer cell lines to irinotecan chemotherapy. Eur. J Med. Chem, 2017, 139: 917-925. (二区，IF= 4.519）[PDF DOWNLOAD] |
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| 151. Jianzhang Wu#, Shoubiao Wu#, Lingyi Shi#, Shanshan Zhang, Jiye Ren, Song Yao, Di yun, Lili Huang, Jiabing Wang, Wulan Li*，Xiaoping Wu*, Peihong Qiu*, Guang Liang. Design, Synthesis, and Evaluation of Asymmetric EF24 Analogues as Potential Anti-Cancer Agents for Lung Cancer. Eur. J Med. Chem, 2017, 125: 1321-1331. (二区，IF= 4.519）[PDF DOWNLOAD] |
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| 150. Song Yao, Kaijing Zhou, Jiabing Wang, Hongen Cao, Lei Yu, Jianzhang Wu*, Peihong Qiu*, Qing Xu*. Synthesis of 2-Subsitituted Quinazolines by CsOH-Mediated Direct Aerobic Oxidative Cyclocondensation of 2-Aminoarylmethanols with Nitriles in Air. Green Chem, 2017, 19(13): 2945-2951. (一区, IF=9.125)[PDF DOWNLOAD] |
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| 149. Chenyu Qiu#, Tingting Zhang#, Wenxin Zhang, Lina Zhou, Bin Yu, Wei Wang, Zhihong Yang, Zhiguo Liu* , Peng Zou*, Guang Liang. Licochalcone A Inhibits the Proliferation of Human Lung Cancer Cell Lines A549 and H460 by Inducing G2/M Cell Cycle Arrest and ER Stress. International Journal of Molecular Sciences, 2017, 18, 1761. (三区，IF= 3.226)[PDF DOWNLOAD] |
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| 148. Lingfeng Chen#, Weitao Fu#, Chen Feng#, Rong Qu, Linjiang Tong, Lulu Zheng, Bo Fang, Yinda Qiu, Jie Hu, Yuepiao Cai, Jianpeng Feng, Hua Xie, Jian Ding*, Zhiguo Liu*, Guang Liang*. Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC. European Journal of Medicinal Chemistry,2017,140: 510-527. (二区，IF= 4.519)[PDF DOWNLOAD] |
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| 147. Xuanxuan Dai, Guilong Guo, Peng Zou, Ri Cui, Weiqian Chen, Xi Chen, Changtian Yin, Wei He, Rajamanickam Vinothkumar, Fan Yang, Xiaohua Zhang*, Guang Liang*. (S)-crizotinib induces apoptosis in human non-small cell lung cancer cells by activating ROS independent of MTH1. Journal of Experimental & Clinical Cancer Research,2017,36(1): 120. (二区，IF= 5.189)[PDF DOWNLOAD] |
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| 146. Gaozhi Chen#, Bing Xiao#, Lingfeng Chen#, Bin Bai, Yali Zhang, Zheng Xu, Lili Fu, Zhiguo Liu, Xiaokun Li*, Yunjie Zhao*, Guang Liang*. Discovery of new MD2-targeted anti-inflammatory compounds for the treatment of sepsis and acute lung injury. European Journal of Medicinal Chemistry, 2017, 139: 726-740. (二区，IF= 4.519)[PDF DOWNLOAD] |
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| 145. Hongjin Chen#, Xi Yang#, Kongqin Lu, Chun Lu, Yunjie Zhao, Suqing Zheng, Jieli Li, Zhangjian Huang, Yi Huang*, Yali Zhang*, Guang Liang. Inhibition of high glucose-induced inflammation and fibrosis by a novel curcumin derivative prevents renal and heart injury in diabetic mice. Toxicology Letters, 2017, 278:48-58. (二区，IF= 3.858)[PDF DOWNLOAD] |
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| 144. Lintao Wang, Jibo Han, Peiren Shan, Shengban You, Xuemei Chen, Yiyi Jin, Jingying Wang, Weijian Huang, Yi Wang*, Guang Liang*. MD2 blockage protects obesity-induced vascular remodeling via activating AMPK/Nrf-2. Obesity, 2017, 25(9): 1532-1539. (二区，IF= 3.873)[PDF DOWNLOAD] |
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| 143. Qilu Fang#, Lintao Wang#, Daona Yang#, Xiong Chen, Xiaoou Shan, Yali Zhang, Hazel Lum, Jingying Wang, Peng Zhong, Guang Liang*, Yi Wang*. Blockade of myeloid differentiation protein 2 prevents obesity-induced inflammation and nephropathy. Journal of Cellular and Molecular Medicine, 2017, 21(12): 3776-3786. (二区，IF= 4.499)[PDF DOWNLOAD] |
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| 142. Lingfeng Chen#, Yiyi Jin#, Weitao Fu, Siyang Xiao, Chen Feng, Bo Fang, Yugui Gu, Chenglong Li,, Yunjie Zhao*, Zhiguo Liu*, Guang Liang*. Design, synthesis and structure-activity relationship analysis of novel thiazolo[3,2-a]pyrimidin derivatives with anti-inflammatory activity in acute lung injury. ChemMedChem, 2017, 12: 1022-1032. (Cover story)(二区，IF= 3.225)[PDF DOWNLOAD] |
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| 141. Lili Fu#, Xiaodong Bao#, Shanshan Li, Lingtian Wang, Zhiguo Liu, Wanzhi Chen, Qinqin Xia*, Guang Liang. Synthesis of sulfonamides from azoles and sodium sulfinates at ambient temperature. Tetrahedron, 2017, 73：2504-2511. (三区，IF= 2.651)[PDF DOWNLOAD] |
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| 140. Jianzhang Wu#, Xiaojing Du#, Wulan Li#, Yangyang Zhou#, Encheng Bai, Yanting Kang, Qiuxiang Chen, Weitao Fu, Di Yun, Qing Xu, Peihong Qiu*, Rong Jin*, Yuepiao Cai*, Guang Liang. A novel non-ATP competitive FGFR1 inhibitor with therapeutic potential on gastric cancer through inhibition of cell proliferation, survival and migration. Apoptosis, 2017, 22: 852-864. (二区，IF= 3.833)[PDF DOWNLOAD] |
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| 139. Christopher Pignanelli, Dennis Ma, Megan Noel, Jesse Ropat, Fadi Mansour, Colin Curran, Simon Pupulin, Kristen Lacrocque, Jianzhang Wu, Guang Liang, Yi Wang* and Siyaram Pandey*. Selective Targeting of Cancer Cells by Oxidative Vulnerabilities with Novel Curcumin Analogs. Scientific Reports, 2017, 7(1):1105. (二区，IF= 4.259)[PDF DOWNLOAD] |
|
| 138. Lihua Wang, Xiwen Chen, Zhuanyun Du, Gefei Li, Mayun Chen, Xi Chen, Guang Liang*, Tongke Chen*. Curcumin suppresses gastric tumor cell growth via ROS-mediated DNA polymerase γdepletion disrupting cellular bioenergetics. Journal of Experimental & Clinical Cancer Research, 2017, 36(1): 47. (二区，IF= 5.189)[PDF DOWNLOAD] |
|
| 137. Lintao Wang#, Zhouqing Huang#, Weijian Huang#, Xuemei Chen, Peiren Shan, Peng Zhong, Zia Khan, Jingying Wang, Qilu Fang, Guang Liang*, Yi Wang*. Inhibition of epidermal growth factor receptor attenuates atherosclerosis via decreasing inflammation and oxidative stress. Scientific Reports, 2017, 8: 45917. (二区，IF= 4.259)[PDF DOWNLOAD] |
|
| 136. Xi Chen, Xuanxuan Dai, Peng Zou, Weiqian Chen, Vinothkumar Rajamanickam, Chen Feng, Weishan Zhuge, Chenyu Qiu, Qingqing Ye, Xiaohua Zhang*, Guang Liang*. Curcuminoid EF24 enhances the anti-tumor activity of Akt inhibitor MK-2206 through ROS-mediated ER stress and mitochondrial dysfunction in gastric cancer. British Journal of Pharmacology, 2017,174(10):1131-1146. (一区，IF= 5.491)[PDF DOWNLOAD] |
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| 135. Zheng Xu#, Yunjie Zhao#, Jingying Wang, Peng Zhong, Qiaoyou Weng, Yuanyuan Qian, Jibo Han, Chunpeng Zou*, Guang Liang*. EGFR Inhibition Attenuates Diabetic Nephropathy through Decreasing ROS and Endoplasmic Reticulum Stress. Oncotarget, 2017, 8(20): 32655-32667. (一区，IF= 5.168)[PDF DOWNLOAD] |
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| 134. Chen Feng#, Yiqun Xia#, Peng Zou#, Miaoshan Shen, Jie Hu, Shilong Ying, Jialing Pan, Zhiguo Liu, Xuanxuan Dai, Weishan Zhuge, Guang Liang*, Yeping Ruan*. Curcumin analogue L48H37 induces apoptosis through ROS-mediated endoplasmic reticulum stress and STAT3 pathways in human lung cancer cells. Molecular Carcinogenesis, 2017, 56: 1765–1777. (二区，IF= 4.185)[PDF DOWNLOAD] |
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| 133. Xiaoou Shan#, Yali Zhang#, Hongjin Chen#, Lili Dong, Beibei Wu, Tingting Xu, Jie Hu, Zhiguo Liu, Wei Wang, Liqin Wu, Zhiguo Feng*, Guang Liang*. Inhibition of epidermal growth factor receptor attenuates LPS-induced inflammation and acute lung injury in rats. Oncotarget, 2017,8(16):26648-26661. (一区，IF= 5.168)[PDF DOWNLOAD] |
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| 132. Zheng Xu#, Weixin Li#, Jibo Han, Chunpeng Zou, Weijian Huang, Weihui Yu, Xiaoou Shan, Hazel Lum, Xiaokun Li*, Guang Liang*. Angiotensin II induces kidney inflammatory injury and fibrosis through binding to myeloid differentiation protein-2 (MD2). Scientific Reports, 2017, 7: 44911. (二区，IF= 4.259)[PDF DOWNLOAD] |
|
| 131. Zhen Wang, Yali Zhang, Bartual Sergio, Jinfeng Luo, Tingting Xu, Wenting Du, Qiuju Xun, Zhengchao Tu, Brekken Rolf, Xiaomei ren, Bullock Alex, Guang Liang*, Xiaoyun Lu*, Ke Ding*. Tetrahydroisoquinoline-7-carboxamide Derivatives as New Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors. ACS Medicinal Chemistry Letters, 2017, 8(3): 327-332. (二区，IF= 3.746)[PDF DOWNLOAD] |
|
| 130. Weitao Fu, Lingfeng Chen, Zhe Wang, Yanting Kang, Chao Wu, Qinqin Xia, Zhiguo Liu, Jianmin Zhou, Guang Liang*, Yuepiao Cai*. Theoretical studies on FGFR isoform selectivity of FGFR1/FGFR4 inhibitors by molecular dynamics simulations and free energy calculations. Physical Chemistry Chemical Physics, 2017, 19(5): 3649-3659. (二区，IF= 4.123)[PDF DOWNLOAD] |
|
| 129. Luqing Ren, Jianjian Tao, Huaicheng Chen, Yang Bian, Xi Yang, Gaozhi Chen, Xin Zhang, Guang Liang, Wencan Wu*, Zongming Song*, Yi Wang1*. Myeloid differentiation protein 2-dependent mechanisms in retinal ischemia-reperfusion injury. Toxicology and Applied Pharmarcology, 2017, 317: 1-11. (二区，IF= 3.791)[PDF DOWNLOAD] |
|
| 128. Yi Wang#, Yuanyuan Qian#, Qilu Fang#, Peng Zhong#, Weixin Li#, Lintao Wang, Weitao Fu, Yali Zhang, Zheng Xu, Xiaokun Li, Guang Liang*. Saturated palmitic acid induces myocardial inflammatory injuries through direct binding to TLR4 accessory protein MD2. Nature Communications, 2017, 8: 13997. (一区，IF= 12.124)[PDF DOWNLOAD] |
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| 127. Jibo Han#, Chunpeng Zou#, Liqin Mei, Yuanyuan Qian, Shengban You, Yong Pan, Zheng Xu, Bin Bai, Weijian Huang*, Guang Liang*. MD2 mediates Angiotensin II-induced cardiac inflammation and remodeling via directly binding to Ang II and activating TLR4/NF-κB signaling pathway. Basic Research in Cardiology, 2017, 112(1): 9. (二区，IF= 5.306)[PDF DOWNLOAD] |
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| 126. Shilong Ying#, Xiaojing Du#, Weitao Fu#, Di Yun, Liping Chen, Yuepiao Cai, Qing Xu, Jianzhang Wu*, Wulan Li*, Guang Liang. Synthesis, biological evaluation, QSAR and molecular dynamics simulation studies of potential Fibroblast Growth Factor Receptor 1 inhibitors for the treatment of gastric cancer. European Journal of Medicinal Chemistry, 2017, 127: 885-899. (二区，IF= 4.519)[PDF DOWNLOAD] |
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| 125. Minxiao Chen#, Bin Zhou#, Peng Zhong, Vinothkumar Rajamanickam, Xuanxuan Dai, Kanchana Karvannan, Huiping Zhou, Xiuhua Zhang*, Guang Liang*. Increased intracellular reactive oxygen species mediates the anti-cancer effects of WZ35 via activating mitochondrial apoptosis pathway in prostate cancer cells. The Prostate, 2017，77(5): 489-504. (二区，IF= 3.82)[PDF DOWNLOAD] |
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| 124. Yali Zhang#, Tingting Xu#, Beibei Wu#, Hongjin Chen, Zheer Pan, Yi Huang, Liqin Mei, Yuanrong Dai, Xing Liu*, Xiaoou Shan*, Guang Liang*. Targeting myeloid differentiation protein 2 by the new chalcone L2H21 protects LPS-induced acute lung injury. Journal of Cellular and Molecular Medicine, 2017,21(4): 746-757. (二区，IF= 4.499)[PDF DOWNLOAD] |
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| 123. Junru Zhang, Zhiguo Feng, Chunhua Wang, Huiping Zhou, Weidong Liu, Karvannan Kanchana, Xuanxuan Dai, Peng Zou, Junlian Gu, Lu Cai*, Guang Liang*. Curcumin derivative WZ35 efficiently suppresses colon cancer progression through inducing ROS production and ER stress-dependent apoptosis. American Journal of Cancer Research, 2017, 7(2):275-288. (二区，IF= 3.264)[PDF DOWNLOAD] |
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| 122. Yan Hu#, Chengguang Zhao#, Hailun Zheng, Kongqin Lu, Dengjian Shi, Zhiguo Liu, Xuanxuan Dai, Yi Zhang, Xiuhua Zhang*, Wanle Hu* and Guang Liang. A novel STAT3 inhibitor HO-3867 induces cell apoptosis by reactive oxygen species-dependent endoplasmic reticulum stress in human pancreatic cancer cells. Anti-Cancer Drugs, 2017, 28:392–400. (四区，IF= 2.32)[PDF DOWNLOAD] |
|
| 2016 |
|
|---|
| 121. Jiao Song, Wenbo Chen, Yunjie Zhao, Chenglong Li, Guang Liang*, Lehao Huang*. Palladium-catalyzed ortho C–H bond alkylation of benzylamides with a-bromo ketones. RSC Advances, 2016, 6: 54984. (二区，IF= 3.289)[PDF DOWNLOAD] |
|
| 120. Yanting Kang#, Wanle Hu#, Encheng Bai, Hailun Zheng, Zhiguo Liu, Jianzhang Wu, Rong Jin*, Chengguang Zhao* , Guang Liang. Curcumin sensitizes human gastric cancer cells to 5-fluorouracil through inhibition of the NFκB survival-signaling pathway. OncoTargets and Therapy,2016,9: 7373-7384. (四区，IF= 2.27)[PDF DOWNLOAD] |
|
| 119. Chenyu Qiu#, Yan Hu#, Ke Wu, Ke Yang, Nan Wang, Yue Ma, Heping Zhu, Yi Zhang, Yunfang Zhou, Chao Chen, Shanshan Li, Lili Fu, Xiuhua Zhang*, Zhiguo Liu*. Synthesis and biological evaluation of allylated mono-carbonyl analogues of curcumin (MACs) as anti-cancer agents for cholangiocarcinoma. Bioorganic & Medicinal Chemistry Letters, 2016，26(24): 5971-5976. (三区，IF= 2.486)[PDF DOWNLOAD] |
|
| 118. Kesong Peng, Yong Pan, Jieli Li, Zia Khan, Mendi Fan, Haimin Yin, Chao Tong, Yunjie Zhao, Guang Liang*, Chao Zheng*. 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) mediates insulin resistance through JNK activation in adipocytes. Scientific Reports, 2016, 6, 37160. (二区，IF= 5.228)[PDF DOWNLOAD] |
|
| 117. Guodong He#, Chen Feng#, Rajamanickam Vinothkumar, Weiqian Chen, Xuanxuan Dai, Xi Chen, Qingqing Ye, Chenyu Qiu, Huiping Zhou, Yi Wang, Guang Liang, Yubo Xie*, Wei Wu*. Curcumin analog EF24 induces apoptosis via ROS-dependent mitochondrial dysfunction in human colorectal cancer cells. Cancer Chemotherapy and Pharmacology, 2016, 78(6): 1151-1161. (三区，IF= 2.824)[PDF DOWNLOAD] |
|
| 116. Jialing Pan#, Tingting Xu#, Fengli Xu, Yali Zhang, Zhiguo Liu, Wenbo Chen, Weitao Fu, Yuanrong Dai, Yunjie Zhao*, Jianpeng Feng*, Guang Liang. Development of resveratrol-curcumin hybrids as potential therapeutic agents for inflammatory lung diseases. European Journal of Medicinal Chemistry, 2016, 125: 478-491. (二区，IF= 3.902)[PDF DOWNLOAD] |
|
| 115. Weiqian Chen, Peng Zou, Zhongwei Zhao, Xi Chen, Xiaoxi Fan, Rajamanickam Vinothkumar, Ri Cui, Fazong Wu, Qianqian Zhang, Guang Liang* and Jiansong Ji*. Synergistic antitumor activity of Rapamycin and EF24 via increasing ROS for the treatment of gastric cancer. Redox Biology, 2016, 10: 78-89. (二区，IF= 6.235)[PDF DOWNLOAD] |
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| 114. Melissa Skibba, Yuanyuan Qian, Yuyan Bao, Junjie Lan, Kesong Peng, Yunjie Zhao, Peng Zhong, Jie Hu, Xiaokun Li*, Guang Liang*. New EGFR inhibitor, 453, prevents renal fibrosis in angiotensin II-stimulated mice. European Journal of Pharmacology, 2016, 789:421-430. (三区，IF= 2.73) |
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| 113. Renyu Lin#, Ziheng Zhang#, Linfeng Chen, Yunfang Zhou, Peng Zou, Chen Feng, Li Wang*, Guang Liang*. Dihydroartemisinin (DHA) induces ferroptosis and causes cell cycle arrest in head and neck carcinoma cells. Cancer Letter, 2016, 381(1):165-75. (二区，IF= 5.992)[PDF DOWNLOAD] |
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| 112. Heping Zhu#, Tingting Xu#, Chenyu Qiu#, Beibei Wu, Yali Zhang, Lingfeng Chen, Qinqin Xia, Chenglong Li, Bin Zhou*, Zhiguo Liu*, Guang Liang. Synthesis and optimization of novel allylated mono-carbonyl analogs of curcumin (MACs) act as potent anti-inflammatory agents against LPS-induced acute lung injury (ALI) in rats.European Journal of Medicinal Chemistry,2016,121: 181-193. (二区，IF= 3.902)[PDF DOWNLOAD] |
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| 111. Zhiguo Liu#, Longguang Tang#, Heping Zhu#, Tingting Xu, Chenyu Qiu, Suqing Zheng, Yugui Gu, Jianpeng Feng, Yali Zhang*, Guang Liang*. Design, synthesis and structure-activity relationship study of novel indole-2-carboxamide derivatives as anti-inflammatory agents for the treatment of sepsis.Journal of Medicinal Chemistry,2016,59(10):4637-50. (一区，IF= 5.589)[PDF DOWNLOAD] |
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| 110. Yali Zhang, Jianzhang Wu, Shilong Ying, Gaozhi Chen, Beibei Wu, Tingting Xu, Zhiguo Liu, Xing Liu, Lehao Huang, Xiaoou Shan, Yuanrong Dai, Guang Liang*. Discovery of new MD2 inhibitor from chalcone derivatives with anti-inflammatory effects in LPS-induced acute lung injury.Scientific Reports, 2016, 6:25130. (二区，IF= 5.228)[PDF DOWNLOAD] |
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| 109. Weixin Li#, Qilu Fang#, Peng Zhong, Lingfeng Chen, Lintao Wang, Yali Zhang, Jun Wang, Xiaokun Li,Yi Wang, Jingying Wang*, Guang Liang*. EGFR Inhibition Blocks Palmitic Acid-induced inflammation in cardiomyocytes and Prevents Hyperlipidemia-induced Cardiac Injury in Mice.Scientific Reports,2016,6: 24580. (二区，IF= 5.228)[PDF DOWNLOAD] |
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| 108. Wei Xu, Yangli Xie, Quan Wang, Xiaofeng Wang, Fengtao Luo, Siru Zhou, Zuqiang Wang, Junlan Huang, Qiaoyan Tan, Min Jin, Huabing Qi, Junzhou Tang, Liang Chen, Xiaolan Du, Chengguang Zhao, Guang Liang*, Lin Chen*. A novel fibroblast growth factor receptor 1 inhibitor protects against cartilage degradation in a murine model of osteoarthritis. Scientific Reports, 2016, 6: 24042. (二区，IF= 5.228)[PDF DOWNLOAD] |
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| 107. Jinming Zhang, Jie Hu, Hon Fai Chan, Melissa Skibba, Guang Liang*, Meiwan Chen*. iRGD Decorated Lipid-polymer Hybrid Nanoparticles for Targeted Co-delivery of Doxorubicin and Sorafenib to Enhance Anti-hepatocellular Carcinoma Efficacy. Nanomedicine, 2016, 12(5): 1303-11. (二区，IF= 5.417) |
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| 106. Gaozhi Chen, Yali zhang, Xing Liu, Qilu Fang, Zhe Wang, Lili Fu, Zhiguo Liu, Yi Wang, Yunjie Zhao, Xiaokun Li, Guang Liang*. Discovery of a new inhibitor of myeloid differentiation 2 from cinnamamide derivatives with anti-inflammatory activity in sepsis and acute lung injury. Journal of Medicinal Chemistry, 2016, 59 (6), 2436–2451. (一区，IF= 5.589)[PDF DOWNLOAD] |
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| 105. Peng Zou#, Yiqun Xia#, Jiansong Ji, Weiqian Chen, Jinsan Zhang, Xi Chen, Vinothkumar Rajamanickam, Gaozhi Chen, Zhe Wang, Lingfeng Chen,Yifeng Wang, Shulin Yang*, Guang Liang*. Piperlongumine as a direct TrxR1 inhibitor with suppressive activity against gastric cancer. Cancer Letter, 2016, 375, 114-126. (二区，IF= 5.992)[PDF DOWNLOAD] |
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| 104. Qilu Fang, Chunpeng Zou, Peng Zhong, Feng Lin, Weixin Li, Lintao Wang, Yali Zhang, Chao Zheng, Yi Wang, Xiaokun Li, Guang Liang*. EGFR mediates hyperlipidemia-induced renal injury via regulating inflammation and oxidative stress: the detrimental role and mechanism of EGFR activation. Oncotarget, 2016, 7(17):24361-73. (一区，IF= 5.008)[PDF DOWNLOAD] |
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| 103. Rong Jin#, Yiqun Xia#, Qiuxiang Chen, Wulan Li, Dahui Chen, Hui Ye, Chengguang Zhao, Xiaojing Du, Dengjian Shi*, Jianzhang Wu*, Guang Liang. Da0324, an inhibitor of nuclear factor-κB activation, demonstrates selective antitumor activity on human gastric cancer cells. Drug Design, Development and Therapy, 2016, 10: 979-995. (三区，IF= 2.881)[PDF DOWNLOAD] |
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| 102. Peng Zou#, Yiqun Xia#, Weiqian Chen, Xi Chen, Shilong Ying, Zhiguo Feng, Tongke Chen, Qingqing Ye, Zhe Wang, Chenyu Qiu, Shulin Yang*, Guang Liang*. EF24 induces ROS-mediated apoptosis via targeting thioredoxin reductase 1 in gastric cancer cells. Oncotarget, 2016, 7(14):18050-64. (一区，IF= 5.008) |
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| 101. Yuanyuan Qian#, Yali Zhang#, Peng Zhong, Kesong Peng, Zheng Xu, Xuemei Chen, Kongqin Lu, Gaozhi Chen, Xiaokun Li, Guang Liang*. Inhibition of inflammation and oxidative stress by an imidazopyridine derivative X22 prevents heart injury from obesity. Journal of Cellular and Molecular Medicine, 2016, 20(8):1427-42. (二区，IF= 4.938) |
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| 100. Weiqian Chen#, Peng Zou#, Zhongwei Zhao, Qiaoyou Weng, Xi Chen, Shilong Ying, Qingqing Ye, Zhe Wang, Jiansong Ji*, Guang Liang*.Selective killing of gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress activation. Oncotarget, 2016, 7(13): 16593-609. (一区，IF= 5.008)[PDF DOWNLOAD] |
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| 99. Xiangting Ge#, Zhiguo Feng#, Tingting Xu, Beibei Wu, Hongjin Chen, Fengli Xu, Lili Fu, Xiaoou Shan, Yuanrong Dai*, Yali Zhang*, Guang Liang. A novel imidazopyridine derivative, X22, attenuates sepsis-induced lung and liver injury by inhibiting the inflammatory response in vitro and in vivo. Drug Design, Development and Therapy, 2016, 10: 1947–1959. (三区，IF= 2.881)[PDF DOWNLOAD] |
|
| 98. Qiaoyou Weng, Luqing Ren, Lu Guo, Yan Hu, Haixia Zhou, Yuyan Bao, Lingfeng Chen, Guang Liang, Yi Wang*, Jichen Ruan*. Curcumin analogue, A13, exhibits anti-leukemia effect via inhibiting STAT3. Tumor Biology, 2016, 37(7):9959-66. (三区，IF= 2.926) |
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| 97. Chengguang Zhao#, Huameng Li#, Huey-Jen Lin, Shulin Yang*, Jiayuh Lin* and Guang Liang. Feedback activation of STAT3 as a cancer drug-resistance mechanism. Trends Pharmacol Sci., 2016: 37 (1): 47-61. (一区，IF= 11.84)[PDF DOWNLOAD] |
|
| 96. Yiqun Xia#, Bixia Weng#, Zhankun Wang, Yanting Kang, Lingyi Shi, Guanqun Huang, Shilong Ying, Xiaojing Du, Qiuxiang Chen, Rong Jin*, Jianzhang Wu*, Guang Liang. W346 inhibits cell growth, invasion, induces cycle arrest and potentiates apoptosis in human gastric cancer cells in vitro through the NF-κB signaling pathway. Tumor Biology, 2016, 37(4):4791-801. (三区，IF=2.926)[PDF DOWNLOAD] |
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| 95. Weitao Fu#, Lingfeng Chen#, Zhe Wang, Chengwei Zhao, Gaozhi Chen, Xing Liu, Yuanrong Dai, Yuepiao Cai, Chenglong Li, Jianmin Zhou*, Guang Liang*. Determination of the binding mode for anti-inflammatory natural product xanthohumol with myeloid differentiation protein 2. Drug Design, Development and Therapy, 2016, 10, 455-463. (三区，IF=2.881)[PDF DOWNLOAD] |
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| 94. Yuanyuan Qian#, Kesong Peng#, Chenyu Qiu, Melissa Skibba, Yi Huang, Zheng Xu, Yali Zhang, Jie Hu, Dandan Liang, Chunpeng Zou, Yi Wang, Guang Liang*. Novel EGFR inhibitor attenuates Ang II-induced Kidney Fibrosis. Journal of Pharmacology and Experimental Therapeutics, 2016, 356(1), 32-42. (二区，IF= 3.76)[PDF DOWNLOAD] |
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| 93. Kesong Peng#, Xinqiao Tian#, Yuanyuan Qian, Melissa Skibba, Chunpeng Zou, Zhiguo Liu, Jingying Wang, Zheng Xu, Xiaokun Li*, Guang Liang*. Novel EGFR inhibitors attenuate cardiac hypertrophy induced by angiotensin II. Journal of Cellular and Molecular Medicine, 2016, 20(3), 482-494. (二区，IF= 4.938)[PDF DOWNLOAD] |
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| 92. Peng Zou, Yiqun Xia, Tongke Chen, Junru Zhang, Zhe Wang, Wenbo Chen, Minxiao Chen, Karvannan Kanchana, Shulin Yang*, Guang Liang*. Selective killing of gastric cancer cells by a small molecule targeting ROS-mediated ER stress activation. Molecular Carcinogenesis, 2016, 55(6): 1073-1086. (二区, IF=4.722)[PDF DOWNLOAD] |
|
| 2015 |
|
|---|
| 91. Xu Shanmei, Chen Minxiao, Chen Wenbo, Hui Junguo, Ji Jiansong, Hu Shuping, Zhou Jianmin*, Wang Yi*, Liang Guang. Chemopreventive effect of chalcone derivative, L2H17, in colon cancer development. BMC Cancer, 2015, 15: 870. (三区，IF= 3.362)[PDF DOWNLOAD] |
|
| 90. Xiuhua Zhang#, Minxiao Chen#, Peng Zou, Karvannan Kanchana, Qiaoyou Weng, Wenbo Chen, Peng Zhong, Jiansong Ji, Huiping Zhou, Langchong He*, Guang Liang*. Curcumin Analog WZ35 Induced Cell Death via ROS-dependent ER Stress and G2/M Cell Cycle Arrest in Human Prostate Cancer Cells. BMC Cancer, 2015, 15: 866. (三区，IF= 3.362)[PDF DOWNLOAD] |
|
| 89. Lei Fan#, Wulan Li#, Shilong Ying, Lingyi Shi, Zhe Wang, Gaozhi Chen, Hui Ye, Xiaoping Wu*, Jianzhang Wu*, Guang Liang, Xiaokun Li. A peptide derivative serves as a fibroblast growth factor 2 antagonist in human gastric cancer. Tumor Biology, 2015, 36 (9), 7233-7241. (三区，IF=3.611)[PDF DOWNLOAD] |
|
| 88. Qilu Fang#, Liancheng Deng#, Lintao Wang, Yali Zhang, Qiaoyou Weng, Haimin Yin, Yong Pan, Chao Tong, Jingying Wang, Guang Liang*.Inhibition of Mitogen-Activated Protein Kinases/Nuclear Factor kB–Dependent Inflammation by a Novel Chalcone Protects the Kidney from High Fat Diet–Induced Injuries in Mice. Journal of Pharmacology and Experimental Therapeutics, 2015, 355(2): 235-46. (二区，IF=3.972)[PDF DOWNLOAD] |
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| 87. Peng Zou, Minxiao Chen, Jiansong Ji, Weiqian Chen, Xi Chen, Shilong Ying, Junru Zhang, Ziheng Zhang, Zhiguo Liu, Shulin Yang*, Guang Liang*. Auranofin induces apoptosis by ROS-mediated ER stress and mitochondrial dysfunction and displayed synergistic lethality with piperlongumine in gastric cancer. Oncotarget, 2015, 6 (34): 36505-36521. (一区，IF=6.359)[PDF DOWNLOAD] |
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| 86. Qiaoyou Weng#, Lili Fu#, Gaozhi Chen, Junguo Hui, Jingjing Song, Jianpeng Feng, Dengjian Shi, Yuepiao Cai, Jiansong Ji*, Guang Liang*. Design, Synthesis, and Anticancer Evaluation of Long-chain Alkoxylated Mono-carbonyl Analogues of Curcumin. European Journal of Medicinal Chemistry, 2015, 103: 44-55. (二区, IF=3.447)[PDF DOWNLOAD] |
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| 85. Leping Zhao#, Yong Pan#, Kesong Peng, Zhe Wang, Jieli Li, Dan Li, Chao Tong*, Yi Wang*, Guang Liang. Inhibition of 11β-HSD1 by LG13 improves glucose metabolism in type 2 diabetic mice. Journal of Molecular Endocrinology, 2015, 55: 119-131. (三区, IF=3.08)PDF DOWNLOAD] |
|
| 84. Qilu Fang, Jingying Wang, Lintao Wang, Yali Zhang, Haimin Yin, Yunzhou Li, Chao Tong, Guang Liang*, Chao Zheng*. Attenuation of inflammatory response by a novel chalcone protects kidney and heart from hyperglycemia-induced injuries in type 1 diabetic mice. Toxicology and Applied Pharmacology, 2015, 288: 179-191. (二区, IF=3.705)[PDF DOWNLOAD] |
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| 83. Lili Dong#, Suqing Zheng#, Yali Zhang, Xin Jiang, Jianzhang Wu, Xiaoqin Zhang, Xiaoou Shan, Dandan Liang, Shilong Ying, Jianpeng Feng* and Guang Liang*. Design, synthesis, and evaluation of semi-conservative mono-carbonyl analogs of curcumin as anti-inflammatory agents against lipopolysaccharide induced acute lung injury. MedChemComm, 2015, 6, 1544-1553. (三区, IF=2.495)[PDF DOWNLOAD] |
|
| 82. Wenbo Chen#, Xiangting Ge#, Fengli Xu, Yali Zhang, Zhiguo Liu, Jialing Pan, Jiao Song, Yuanrong Dai, Jianmin Zhou*, Jianpeng Feng*, Guang Liang. Design, synthesis and biological evaluation of paralleled Aza resveratrol–chalcone compounds as potential anti-inflammatory agents for the treatment of acute lung injury. Bioorganic & Medicinal Chemistry Letters, 2015, 25, 2998-3004. (三区, IF=2.42)[PDF DOWNLOAD] |
|
| 81. Yi Wang#, Xiaoou Shan#, Gaozhi Chen, Lili Jiang, Zhe Wang, Qilu Fang, Xing Liu, Jingying Wang, Yali Zhang, Wencan Wu, Guang Liang*. MD-2 as the target of a novel small molecule, L6H21, in the attenuation of LPS-induced inflammatory response and sepsis. British Journal of Pharmacology, 2015, 172(17): 4391-4405. (二区, IF=4.842)[PDF DOWNLOAD] |
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| 80. Zhe Wang#, Peng Zou#, Chenglong Li, Wenfei He, Bing Xiao, Qilu Fang, Wenbo Chen, Suqing Zheng, Yunjie Zhao*, Yuepiao Cai* and Guang Liang. Synthesis and biological evaluation of novel semi-conservative mono-carbonyl analogs of curcumin as anti-inflammatory agents. MedChemComm, 2015, 6, 1328-1339. (三区, IF=2.495)[PDF DOWNLOAD] |
|
| 79. Jianzhang Wu, Zhijian Cai, XiaoyanWei, Minxiao Chen, Shilong Ying, Lingyi Shi, Ren-Ai Xu, Fan He, Guang Liang, and Xiuhua Zhang*. Anti-Lung Cancer Activity of the Curcumin Analog JZ534 In Vitro. BioMed Research International, 2015: 504529(三区, IF=1.579).[PDF DOWNLOAD] |
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| 78. Jie Hu#, Yali Zhang#, Lili Dong, Zhe Wang, Lingfeng Chen, Dandan Liang, Dengjian Shi, Xiaoou Shan and Guang Liang*. Design, Synthesis, and Biological Evaluation of Novel Quinazoline Derivatives as Anti-inflammatory Agents against Lipopolysaccharide-induced Acute Lung Injury in Rats. chemical biology & drug design, 2015, 85:672-684. (三区, IF=2.485)[PDF DOWNLOAD] |
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| 77. Weixin Li, Lintao Wang, Weijian Huang, Melissa Skibba, Qilu Fang, Longteng Xie, Tiemin Wei, Zhiguo Feng, Guang Liang*. Inhibition of ROS and inflammation by an imidazopyridine derivative X22 attenuates high fat diet-induced arterial injuries. Vascular Pharmacology, 2015, 72:153-162. (三区, IF=3.635)[PDF DOWNLOAD] |
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| 76. Zhe Wang#, Gaozhi Chen#, Lingfeng Chen, Xing Liu, Weitao Fu, Yali Zhang, Chenglong Li, Guang Liang* and Yuepiao Cai*. Insights into the binding mode of curcumin to MD-2: studies from molecular docking, molecular dynamics simulations and experimental assessments. Molecular BioSystems, 2015, 11,1933-1938. (三区, IF=3.21)[PDF DOWNLOAD] |
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| 75. Yang Bian#, Luqing Ren#, Lei Wang, Shanmei Xu, Jianjian Tao, Xiuhua Zhang, Yi Huang, Yuanyuan Qian, Xin Zhang, Zongming Song, Wencan Wu*, Yi Wang*, Guang Liang. A novel imidazopyridine derivative, X22, prevents the retinal ischemia-reperfusion injury via inhibition of MAPKs. Experimental Eye Research, 2015, 135: 26-36. (二区，IF=2.709)[PDF DOWNLOAD] |
|
| 74. Chengguang Zhao, Hui Xiao, Xiaojuan Wu, Chenglong Li, Guang Liang, Shulin Yang,* and Jiayuh Lin*. Rational combination of MEK inhibitor and the STAT3 pathway modulator for the therapy in K-Ras mutated pancreatic and colon cancer cells.Oncotarget, 2015, 6(16): 14472-87. (一区，IF=6.359)[PDF DOWNLOAD] |
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| 73. Yi Wang#, Xiaoou Shan#, Yuanrong Dai, Lili Jiang, Gaozhi Chen, Yali Zhang, Zhe Wang, Lili Dong, Jianzhang Wu, Guilong Guo*, Guang Liang*. Curcumin analog L48H37 prevents LPS-induced TLR4 signaling pathway activation and sepsis via targeting MD2.Journal of Pharmacology and Experimental Therapeutics, 2015, 353:539-550. (二区，IF=3.972)[PDF DOWNLOAD] |
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| 72. Jianzhang Wu#, Tao Wei#, Qinqin Tang, Bixia Weng, Wulan Li, Xin Jiang, Ting Ding, Xiaokun Li, Guang Liang, Yuepiao Cai*, Jiansong Ji*. Discovery and anti-cancer evaluation of two novel non-ATP-competitive FGFR1 inhibitors in non-small-cell lung cancer.BMC Cancer, 2015, 15(1): 276. (三区，IF=3.362)[PDF DOWNLOAD] |
|
| 71. Yali Zhang#, Dan dan Liang#, Lili Dong, Xiangting Ge, Fengli Xu, Wenbo Chen, Yuanrong Dai, Huameng Li, Peng Zou, Shulin Yang*, Guang Liang*. Anti-inflammatory effects of novel curcumin analogs in experimental acute lung injury.Respiratory Research, 2015, 16: 43. (二区，IF=3.093)[PDF DOWNLOAD] |
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| 70. Dan dan Liang#, Peng Zhong#, Jie Hu, Feng Lin, Yuanyuan Qian, Zheng Xu, Jingying Wang, Chunlai Zeng, Xiaokun Li, Guang Liang*. EGFR inhibition protects cardiac damage and remodeling through attenuating oxidative stress in STZ-induced diabetic mouse model.Journal of Molecular and Cellular Cardiology, 2015, 82: 63-74.[二区，IF=4.655，With a commentary in the same issue （Zheng Xu, Lu Cai. Diabetic cardiomyopathy: Role of epidermal growth factor receptor tyrosine kinase, Journal of Molecular Cellular Cardiology, 2015, 84: 10-12)[PDF DOWNLOAD] |
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| 69. Peng Zhong, Lianpin Wu, Yuanyuan Qian, Qilu Fang, Dandan Liang, Jingying Wang, Chunlai Zeng, Yi Wang *, Guang Liang*. Blockage of ROS and NF-kB-mediated inflammation by a new chalcone L6H9 protects cardiomyocytes from hyperglycemia-induced injuries.BBA - Molecular Basis of Disease, 2015, 1852: 1230-1241. (二区，IF=4.882)[PDF DOWNLOAD] |
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| 68. Chengguang Zhao#, Jianpeng Feng#, Mingming Zuo#, Jianfeng Zhao, Shanmei Xu, Suqing Zheng, Yali Zhang, Qinqin Tang, Zhongqiu Lu, Guang Liang* and Jianmin Zhou*. Synthesis and Biological Evaluation of Acetylenic Chalcones as Novel Anti-Inflammatory Agents. Med Chem, 2015, 11(6): 567-72. (四区，IF=1.402)[PDF DOWNLOAD] |
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| 67. Yuanyuan Qian#, Peng Zhong#, Dan dan Liang, Zheng Xu, Melissa Skibba, Chunlai Zeng, Xiaokun Li, Tiemin Wei, Lianpin Wu*, Guang Liang*. A newly designed curcumin analog Y20 mitigates cardiac injury via anti-inflammatory and anti-oxidant actions in obese rats. Plos One, 2015, 10(3): e0120215. (三区，IF=3.234)[PDF DOWNLOAD] |
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| 66. Jianpeng Feng#, Bing Xiao#, Wenbo Chen, Ting Ding, Lingfeng Chen, Pengtian Yu, Fengli Xu, Huajie Zhang*, Zhiguo Liu*, Guang Liang.Synthesis and anti-inflammatory evaluation of novel C66 analogs for the treatment of LPS-induced acute lung injury. Chemical Biology and Drug Design, 2015, Oct; 86(4): 753-63. (三区，IF=2.485)[PDF DOWNLOAD] |
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| 65. Peng Zou#, Junru Zhang, Yiqun Xia, Karvannan Kanchana, Guilong Guo, Wenbo Chen, Yi Huang, Zhe Wang, Shulin Yang*, Guang Liang*. ROS generation mediates the anti-cancer effects of WZ35 via activating JNK and ER stress apoptotic pathways in gastric cancer. Oncotarget, 2015, 6(8): 5860-5876. (一区，IF=6.359)[PDF DOWNLOAD] |
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| 64. Chaochao Xu#, Wulan Li#, Peihong Qiu, Yiqun Xia, Xiaojing Du, Fen Wang, Lailai Shen, Qiuxiang Chen, Yunjie Zhao, Jin Rong*, Jianzhang Wu*, Guang Liang, Xiaokun Li.The therapeutic potential of a novel non-ATP-competitive fibroblast growth factor receptor 1 inhibitor on gastric cancer. Anti-Cancer Drugs, 2015, 26(4): 379-87. (三区，IF=1.784)[PDF DOWNLOAD] |
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| 63. Chengguang zhao#, Yali Zhang#, Peng Zou, Jian Wang, Wenfei He, Dengjian Shi, Huameng Li, Guang Liang*, Shulin Yang*. Synthesis and biological evaluation of a novel class of curcumin analogs as anti-inflammatory agents for prevention and treatment of sepsis in mouse model.Drug Design, Development and Therapy, 2015, 9, 1663–1678.(三区，IF=3.028)[PDF DOWNLOAD] |
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| 62. Pengtian Yu#, Lili Dong#, Yali Zhang, Wenbo Chen, Shanmei Xu, Zhe Wang, Xiaoou Shan, Jianmin Zhou*, Zhiguo Liu*, Guang Liang.Design, synthesis and biological activity of novel asymmetric C66 analogs as anti-inflammatory agents for the treatment of acute lung injury.European Journal of Medicinal Chemistry, 2015, 94: 436-446.(二区，IF=3.447)[PDF DOWNLOAD] |
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| 61. Weixin Li#, Mingchai Wu#, Longguang Tang, Yong Pan, Zhiguo Liu, Chunlai Zeng, Jingying Wang, Tiemin Wei*, Guang Liang*. Novel curcumin analogue 14p protects against myocardial ischemia reperfusion injury through Nrf2-activating anti-oxidative activity.Toxicology and Applied Pharmacology,2015, 282(2):175-183. (二区，IF=3.705)[PDF DOWNLOAD] |
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| 60. Chunlai Zeng#, Peng Zhong#, Yunjie Zhao, Karvannan Kanchana, Yali Zhang, Zia A. Khan, Subrata Chakrabarti, Lianpin Wu, Jingying Wang, Guang Liang*. Curcumin protects hearts from FFA-induced injury by activating Nrf2 and inactivating NF-κB both in vitro and in vivo. Journal of Molecular and Cellular Cardiology, 2015, 79, 1-12.(二区，IF=4.655)[PDF DOWNLOAD] |
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| 59. Qilu Fang#, Leping Zhao#, Yi Wang, Yali Zhang, Yong Pan, Karvannan Kanchana, Jingying Wang, Chao Tong, Dan Li*, Guang Liang*. A novel chalcone derivative attenuates the diabetes-induced renal injury via inhibition of high glucose-mediated inflammatory response and macrophage infiltration. Toxicology and Applied Pharmacology, 2015, 282(2): 129-138.(二区，IF=3.705)[PDF DOWNLOAD] |
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| 2014 |
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| 58. Yali Zhang#, Xin Jiang#, Kesong Peng, Chengwei Chen, Lili Fu, Zhe Wang, Jianpeng Feng, Zhiguo Liu, Huajie Zhang, Guang Liang*,Zheer Pan*. Discovery and evaluation of novel anti-inflammatory derivatives of natural bioactive curcumin. Drug Design, Development and Therapy, 2014, 8, 2161–2171.(三区，IF=3.49)[PDF DOWNLOAD] |
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| 57. Gaozhi Chen#, Qiaoyou Weng#, Lili Fu, Zhe Wang, Pengtian Yu, Zhiguo Liu, Xiaokun Li, Huajie Zhang*, Guang Liang*. Synthesis and biological evaluation of novel oxindole-based RTK inhibitors as anti-cancer agents. Bioorganic and Medicinal Chemistry, 2014, 22, 6953–6960.(三区，IF=2.90)[PDF DOWNLOAD] | |
| 56. Gaozhi Chen#, Lili Jiang#, Lili Dong, Zhe Wang, Fengli Xu, Ting Ding, Lili Fu, Qilu Fang, Zhiguo Liu, Xiaoou Shan*, Guang Liang*. Synthesis and biological evaluation of novel indole-2-one and 7-aza-2-oxindole derivatives as anti-inflammatory agents. Drug Design, Development and Therapy, 2014, 8, 1869–1892. (三区，IF=3.49)[PDF DOWNLOAD] |
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| 55. Yi Wang#, Hui Wang, Luqing Ren, Qiaoyou Weng, Yuyan Bao, Haishan Tian, YongguangYang*, Xiaokun Li*. Non-mitogenic form of acidic fibroblast growth factor protects against graft-versus-host disease without accelerating leukemia.International Immunopharmacology, 2014, 23 (2): 395-9. (三区，IF=2.71)[PDF DOWNLOAD] |
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| 54. Yiqun Xia#, Xiaoyan Wei#, Wulan Li#, Karvannan Kanchana, Chaochao Xu, Dahui Chen, Peihong Chou, Rong Jin*, Jianzhang Wu*, Guang Liang. Curcumin Analogue A501 induces G2/M Arrest and Apoptosis in Non-small Cell Lung Cancer Cells. Asian Pacific Journal of Cancer Prevention, 2014, 15(16), 6893-6898. (四区，IF=1.50)[PDF DOWNLOAD] |
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| 53. Lei Fan#, Hang Xie#, Lingzi Chen#, Hui Ye, Shilong Ying, Cong Wang, Xiaoping Wu, Wulan Li*, Jianzhang Wu*, Guang Liang, Xiaokun Li. A novel FGF2 antagonist peptide P8 with potent antiproliferation activity, Tumor Biol, 2014, 35(10): 10571-9 . (三区，IF=2.52)[PDF DOWNLOAD] |
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| 52. Jianzhang Wu#, Jiansong Ji#, Bixia Weng, Peihong Qiu, Karvannan Kanchana, Tao Wei, Yi Wang, Yuepiao Cai, Xiaokun Li and Guang Liang*. Discovery of novel non-ATP competitive FGFR1 inhibitors and evaluation of their anti-tumor activity in non-small cell lung cancer in vitro and in vivo, Oncotarget, 2014, 5(12), 4543-4553. (一区，IF=6.64)[PDF DOWNLOAD] |
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| 51. Yali Zhang#, Leping Zhao#, Jianzhang Wu#, Xin Jiang, Lili Dong, Fengli Xu, Yuanrong Dai, Peng Zou, Xiaoou Shan*, Shulin Yang*, Guang Liang. Synthesis and evaluation of a series of novel asymmetrical curcumin analogs for the treatment of inflammation, Molecules, 2014, 19(6), 7287-7307. (三区，IF=2.43)[PDF DOWNLOAD] |
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| 50. Pan Yong, Wang Yi, Zhao Yunjie, Peng Kesong, Li Weixin, Wang Yonggang, Zhang Jingjing, Zhou Shanshan, Liu Quan, Li Xiaokun, Cai Lu, Guang Liang*. Inhibition of JNK phosphorylation by a novel curcumin analog prevents high glucose-induced inflammation and apoptosis in cardiomyocytes and the development of diabetic cardiomyopathy, Diabetes, 2014, 63:3497–3511. [一区，IF=8.0，With a commentary in the same issue （Jun Ren, James R. Sowers. Application of a Novel Curcumin Analog in the Management of Diabetic Cardiomyopathy, Diabetes, 2014;63:3166–3168) ][PDF DOWNLOAD] |
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| 49. Yali Zhang#, Chengguang Zhao#, Wenfei He#, Zhe Wang, Qilu Fang, Bing Xiao, Zhiguo Liu, Guang Liang*, Shulin Yang*. Discovery and evaluation of asymmetrical monocarbonyl analogs of curcumin as anti- inflammatory agents, Drug Design, Development and Therapy, 2014, 8: 373–382. (三区，IF=3.49)[PDF DOWNLOAD] |
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| 48. Yong Pan#, Yi Huang#, Zhe Wang, Qilu Fang, Yusheng Sun, Chao Tong, Kesong Peng, Yangwei Wang, Lining Miao, Lu Cai, Yunjie Zhao, Guang Liang*. Inhibition of MAPK-mediated ACE expression by compound C66 prevents STZ-induced diabetic nephropathy, J Cell Mol Med, 2014, 18(2): 231-241. (二区，IF=4.75)[PDF DOWNLOAD] |
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| 47. Yi Wang#, Yuepiao Cai#, Jiansong Ji#, Zhiguo Liu, Chengguang Zhao, Yunjie Zhao, Tao Wei, Xueqian Shen, Xiuhua Zhang, Xiaokun Li*, Guang Liang*. Discovery and identification of new non-ATP competitive FGFR1 inhibitors with therapeutic potential on non-small-cell lung cancer. Cancer Letters, 2014, 344, 82–89 (二区，IF=4.5)[PDF DOWNLOAD] |
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| 46. Zhiguo Liu#, Longguang Tang#, Peng Zou#, Yali Zhang, Zhe Wang, Qilu Fang, Lili Jiang, Gaozhi Chen, Zheng Xu, Huajie Zhang*, Guang Liang*. Synthesis and biological evaluation of allylated and prenylated mono-carbonyl analogues of curcumin as anti-inflammatory agents, European Journal of Medicinal Chemistry, 2014, 74(3), 671-682. (二区，IF=3.50)[PDF DOWNLOAD] |
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